actin filament-based process Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description Any cellular process that depends upon or alters the actin cytoskeleton, that part of the cytoskeleton comprising actin filaments and their associated proteins. (Gene Ontology, GO_0030029)
External Link http://amigo.geneontology.org/amigo/term/GO:0030029
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Genes

318 genes participating in the actin filament-based process biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ABLIM2 actin binding LIM protein family, member 2
ABLIM3 actin binding LIM protein family, member 3
ABR active BCR-related
ACTA1 actin, alpha 1, skeletal muscle
ACTC1 actin, alpha, cardiac muscle 1
ACTG1 actin gamma 1
ACTN2 actinin, alpha 2
ACTN3 actinin, alpha 3 (gene/pseudogene)
ADD1 adducin 1 (alpha)
ADD2 adducin 2 (beta)
ADRA2A adrenoceptor alpha 2A
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
AMOT angiomotin
ANKRD1 ankyrin repeat domain 1 (cardiac muscle)
ANTXR1 anthrax toxin receptor 1
AQP1 aquaporin 1 (Colton blood group)
ARF6 ADP-ribosylation factor 6
ARFIP2 ADP-ribosylation factor interacting protein 2
ARHGAP26 Rho GTPase activating protein 26
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa
ARRB1 arrestin, beta 1
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1
ATXN3 ataxin 3
BCL6 B-cell CLL/lymphoma 6
BCR breakpoint cluster region
BMP10 bone morphogenetic protein 10
BRK1 BRICK1, SCAR/WAVE actin-nucleating complex subunit
BRSK2 BR serine/threonine kinase 2
CALR calreticulin
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast)
CAPN10 calpain 10
CAPN3 calpain 3, (p94)
CAPZB capping protein (actin filament) muscle Z-line, beta
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle)
CASQ2 calsequestrin 2 (cardiac muscle)
CDC42 cell division cycle 42
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CDC42BPG CDC42 binding protein kinase gamma (DMPK-like)
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CDK5 cyclin-dependent kinase 5
CFL1 cofilin 1 (non-muscle)
CFL2 cofilin 2 (muscle)
CFLAR CASP8 and FADD-like apoptosis regulator
CNN1 calponin 1, basic, smooth muscle
CNN2 calponin 2
CNN3 calponin 3, acidic
CORO1A coronin, actin binding protein, 1A
CORO1B coronin, actin binding protein, 1B
CORO1C coronin, actin binding protein, 1C
CORO2A coronin, actin binding protein, 2A
CORO2B coronin, actin binding protein, 2B
CORO6 coronin 6
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein)
CTTN cortactin
CUL3 cullin 3
CXADR coxsackie virus and adenovirus receptor
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CYTH2 cytohesin 2
DAAM1 dishevelled associated activator of morphogenesis 1
DAAM2 dishevelled associated activator of morphogenesis 2
DES desmin
DIAPH3 diaphanous-related formin 3
DLC1 DLC1 Rho GTPase activating protein
DLG1 discs, large homolog 1 (Drosophila)
DMD dystrophin
DMTN dematin actin binding protein
DOCK2 dedicator of cytokinesis 2
DSTN destrin (actin depolymerizing factor)
DTNBP1 dystrobrevin binding protein 1
DYNLL1 dynein, light chain, LC8-type 1
EHD2 EH-domain containing 2
ELMO1 engulfment and cell motility 1
EMP2 epithelial membrane protein 2
EPB41 erythrocyte membrane protein band 4.1
EPB41L1 erythrocyte membrane protein band 4.1-like 1
EPB41L2 erythrocyte membrane protein band 4.1-like 2
EPB41L3 erythrocyte membrane protein band 4.1-like 3
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EPS8 epidermal growth factor receptor pathway substrate 8
F11R F11 receptor
FAM101B family with sequence similarity 101, member B
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FBXO8 F-box protein 8
FER fer (fps/fes related) tyrosine kinase
FGD1 FYVE, RhoGEF and PH domain containing 1
FGD2 FYVE, RhoGEF and PH domain containing 2
FGD3 FYVE, RhoGEF and PH domain containing 3
FGD4 FYVE, RhoGEF and PH domain containing 4
FGD5 FYVE, RhoGEF and PH domain containing 5
FGD6 FYVE, RhoGEF and PH domain containing 6
FGF10 fibroblast growth factor 10
FGF7 fibroblast growth factor 7
FHL3 four and a half LIM domains 3
FHOD3 formin homology 2 domain containing 3
FLII flightless I homolog (Drosophila)
FLNA filamin A, alpha
FLNB filamin B, beta
FMNL1 formin-like 1
FMNL2 formin-like 2
FMNL3 formin-like 3
FNBP1L formin binding protein 1-like
FOXJ1 forkhead box J1
FRK fyn-related Src family tyrosine kinase
FRMD6 FERM domain containing 6
FSCN1 fascin actin-bundling protein 1
FSCN2 fascin actin-bundling protein 2, retinal
GAS2L3 growth arrest-specific 2 like 3
GPR65 G protein-coupled receptor 65
GSN gelsolin
HIP1 huntingtin interacting protein 1
HIP1R huntingtin interacting protein 1 related
HRAS Harvey rat sarcoma viral oncogene homolog
INF2 inverted formin, FH2 and WH2 domain containing
INPP5K inositol polyphosphate-5-phosphatase K
INSRR insulin receptor-related receptor
IQSEC1 IQ motif and Sec7 domain 1
IQSEC2 IQ motif and Sec7 domain 2
IQSEC3 IQ motif and Sec7 domain 3
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB5 integrin, beta 5
ITPKA inositol-trisphosphate 3-kinase A
KCTD13 potassium channel tetramerization domain containing 13
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLHL1 kelch-like family member 1
KLHL17 kelch-like family member 17
KLHL41 kelch-like family member 41
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT19 keratin 19, type I
KRT8 keratin 8, type II
LDB3 LIM domain binding 3
LIMCH1 LIM and calponin homology domains 1
LIMK1 LIM domain kinase 1
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LMOD1 leiomodin 1 (smooth muscle)
LMOD2 leiomodin 2 (cardiac)
LMOD3 leiomodin 3 (fetal)
LPIN1 lipin 1
LURAP1 leucine rich adaptor protein 1
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K19 mitogen-activated protein kinase kinase kinase 19
MEF2A myocyte enhancer factor 2A
MICALL2 MICAL-like 2
MINK1 misshapen-like kinase 1
MKLN1 muskelin 1, intracellular mediator containing kelch motifs
MOB2 MOB kinase activator 2
MON2 MON2 homolog (S. cerevisiae)
MRAS muscle RAS oncogene homolog
MTSS1 metastasis suppressor 1
MYBPC1 myosin binding protein C, slow type
MYBPC2 myosin binding protein C, fast type
MYBPC3 myosin binding protein C, cardiac
MYH10 myosin, heavy chain 10, non-muscle
MYH11 myosin, heavy chain 11, smooth muscle
MYH14 myosin, heavy chain 14, non-muscle
MYH2 myosin, heavy chain 2, skeletal muscle, adult
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic
MYH4 myosin, heavy chain 4, skeletal muscle
MYH6 myosin, heavy chain 6, cardiac muscle, alpha
MYH7 myosin, heavy chain 7, cardiac muscle, beta
MYH8 myosin, heavy chain 8, skeletal muscle, perinatal
MYH9 myosin, heavy chain 9, non-muscle
MYL1 myosin, light chain 1, alkali; skeletal, fast
MYL2 myosin, light chain 2, regulatory, cardiac, slow
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle
MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle
MYLK3 myosin light chain kinase 3
MYO18A myosin XVIIIA
MYO1B myosin IB
MYO1E myosin IE
MYO5A myosin VA (heavy chain 12, myoxin)
MYO6 myosin VI
MYO7A myosin VIIA
MYO9B myosin IXB
MYOZ1 myozenin 1
MYPN myopalladin
NCKAP1 NCK-associated protein 1
NCKAP1L NCK-associated protein 1-like
NEB nebulin
NEURL2 neuralized E3 ubiquitin protein ligase 2
NF1 neurofibromin 1
NF2 neurofibromin 2 (merlin)
NISCH nischarin
NKX2-5 NK2 homeobox 5
NPHP1 nephronophthisis 1 (juvenile)
NPHP4 nephronophthisis 4
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NUAK2 NUAK family, SNF1-like kinase, 2
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OBSL1 obscurin-like 1
OPHN1 oligophrenin 1
PACSIN2 protein kinase C and casein kinase substrate in neurons 2
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PARD3 par-3 family cell polarity regulator
PARVA parvin, alpha
PARVB parvin, beta
PARVG parvin, gamma
PDCD10 programmed cell death 10
PDGFA platelet-derived growth factor alpha polypeptide
PDGFB platelet-derived growth factor beta polypeptide
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDLIM7 PDZ and LIM domain 7 (enigma)
PDPK1 3-phosphoinositide dependent protein kinase 1
PFDN1 prefoldin subunit 1
PFN1 profilin 1
PFN2 profilin 2
PFN3 profilin 3
PHACTR1 phosphatase and actin regulator 1
PHACTR4 phosphatase and actin regulator 4
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLEK pleckstrin
PLEK2 pleckstrin 2
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRKCDBP protein kinase C, delta binding protein
PRKCZ protein kinase C, zeta
PRKG1 protein kinase, cGMP-dependent, type I
PROX1 prospero homeobox 1
PTK2B protein tyrosine kinase 2 beta
PTK6 protein tyrosine kinase 6
PTK7 protein tyrosine kinase 7 (inactive)
PTPN1 protein tyrosine phosphatase, non-receptor type 1
RAB13 RAB13, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RACGAP1 Rac GTPase activating protein 1
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
RAN RAN, member RAS oncogene family
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1
RAP2A RAP2A, member of RAS oncogene family
RHOA ras homolog family member A
RHOG ras homolog family member G
RHOJ ras homolog family member J
RHOQ ras homolog family member Q
RHOU ras homolog family member U
RICTOR RPTOR independent companion of MTOR, complex 2
RND3 Rho family GTPase 3
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
S100A9 S100 calcium binding protein A9
S1PR1 sphingosine-1-phosphate receptor 1
SCIN scinderin
SDAD1 SDA1 domain containing 1
SDCBP syndecan binding protein (syntenin)
SELE selectin E
SH2B2 SH2B adaptor protein 2
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SHROOM3 shroom family member 3
SHROOM4 shroom family member 4
SIPA1L1 signal-induced proliferation-associated 1 like 1
SIX4 SIX homeobox 4
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SORBS1 sorbin and SH3 domain containing 1
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like
SPIRE1 spire-type actin nucleation factor 1
SPIRE2 spire-type actin nucleation factor 2
SPTBN5 spectrin, beta, non-erythrocytic 5
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRF serum response factor (c-fos serum response element-binding transcription factor)
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites
SSH1 slingshot protein phosphatase 1
SSH2 slingshot protein phosphatase 2
STRIP1 striatin interacting protein 1
SUN2 Sad1 and UNC84 domain containing 2
SYNE2 spectrin repeat containing, nuclear envelope 2
TAOK2 TAO kinase 2
TCAP titin-cap
TESK2 testis-specific kinase 2
TLN1 talin 1
TMOD1 tropomodulin 1
TMOD2 tropomodulin 2 (neuronal)
TMOD3 tropomodulin 3 (ubiquitous)
TMOD4 tropomodulin 4 (muscle)
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TNIK TRAF2 and NCK interacting kinase
TNNC1 troponin C type 1 (slow)
TNNC2 troponin C type 2 (fast)
TNNI1 troponin I type 1 (skeletal, slow)
TNNI2 troponin I type 2 (skeletal, fast)
TNNI3 troponin I type 3 (cardiac)
TNNT1 troponin T type 1 (skeletal, slow)
TNNT2 troponin T type 2 (cardiac)
TNNT3 troponin T type 3 (skeletal, fast)
TNXB tenascin XB
TPM1 tropomyosin 1 (alpha)
TPM2 tropomyosin 2 (beta)
TPM3 tropomyosin 3
TPM4 tropomyosin 4
TRIOBP TRIO and F-actin binding protein
TRIP10 thyroid hormone receptor interactor 10
TRPM7 transient receptor potential cation channel, subfamily M, member 7
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TTN titin
VIL1 villin 1
VIM vimentin
WAS Wiskott-Aldrich syndrome
WASF2 WAS protein family, member 2
WASL Wiskott-Aldrich syndrome-like
WIPF1 WAS/WASL interacting protein family, member 1
XIRP1 xin actin binding repeat containing 1
XIRP2 xin actin binding repeat containing 2
ZYX zyxin