actin cytoskeleton Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes. (Gene Ontology, GO_0015629)
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Genes

365 proteins localized to the actin cytoskeleton cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 0.663342
SEPT7 septin 7 0.663342
SPTBN5 spectrin, beta, non-erythrocytic 5 0.663342
SPTBN4 spectrin, beta, non-erythrocytic 4 0.663342
SPTBN2 spectrin, beta, non-erythrocytic 2 0.663342
SEPT9 septin 9 0.663342
MYO3A myosin IIIA 0.663342
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa 0.663342
DMTN dematin actin binding protein 0.663342
TNNI3 troponin I type 3 (cardiac) 0.663342
TNNI2 troponin I type 2 (skeletal, fast) 0.663342
PEAK1 pseudopodium-enriched atypical kinase 1 0.663342
LPXN leupaxin 0.663342
MAEA macrophage erythroblast attacher 0.663342
CD2AP CD2-associated protein 0.663342
MYO9B myosin IXB 0.663342
VIL1 villin 1 0.663342
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 0.663342
HNRNPK heterogeneous nuclear ribonucleoprotein K 0.663342
ANLN anillin, actin binding protein 0.663342
ARHGAP6 Rho GTPase activating protein 6 0.663342
FYB FYN binding protein 0.663342
SH3PXD2A SH3 and PX domains 2A 0.663342
ACTC1 actin, alpha, cardiac muscle 1 0.663342
ACTA1 actin, alpha 1, skeletal muscle 0.663342
KLHL2 kelch-like family member 2 0.663342
DAPK1 death-associated protein kinase 1 0.663342
IFIT5 interferon-induced protein with tetratricopeptide repeats 5 0.663342
CLIC4 chloride intracellular channel 4 0.663342
CLIC5 chloride intracellular channel 5 0.663342
TNNT2 troponin T type 2 (cardiac) 0.663342
TNNT3 troponin T type 3 (skeletal, fast) 0.663342
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 0.663342
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 0.663342
MYL7 myosin, light chain 7, regulatory 0.663342
FBLIM1 filamin binding LIM protein 1 0.663342
PTK2 protein tyrosine kinase 2 0.663342
DBN1 drebrin 1 0.663342
MYLK myosin light chain kinase 0.663342
CORO2B coronin, actin binding protein, 2B 0.663342
MYO1A myosin IA 0.663342
LUZP6 leucine zipper protein 6 0.663342
MYO1C myosin IC 0.663342
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 0.663342
MYO1E myosin IE 0.663342
MYO9A myosin IXA 0.663342
TLN2 talin 2 0.663342
TPM4 tropomyosin 4 0.663342
LIMA1 LIM domain and actin binding 1 0.663342
BIN2 bridging integrator 2 0.663342
SVIL supervillin 0.663342
C10ORF90 chromosome 10 open reading frame 90 0.663342
CNN2 calponin 2 0.663342
PGM5 phosphoglucomutase 5 0.663342
SNAP25 synaptosomal-associated protein, 25kDa 0.663342
PXN paxillin 0.663342
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.663342
CORO1A coronin, actin binding protein, 1A 0.663342
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial) 0.663342
FSCN1 fascin actin-bundling protein 1 0.663342
TPM3 tropomyosin 3 0.663342
MYO1F myosin IF 0.663342
MYH10 myosin, heavy chain 10, non-muscle 0.663342
MYH9 myosin, heavy chain 9, non-muscle 0.663342
ACTA2 actin, alpha 2, smooth muscle, aorta 0.663342
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.663342
MYH2 myosin, heavy chain 2, skeletal muscle, adult 0.663342
NEBL nebulette 0.663342
TRIOBP TRIO and F-actin binding protein 0.663342
AMOT angiomotin 0.663342
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) 0.663342
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) 0.663342
DCTN2 dynactin 2 (p50) 0.663342
MYO18B myosin XVIIIB 0.663342
MYO18A myosin XVIIIA 0.663342
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 0.663342
MARK2 MAP/microtubule affinity-regulating kinase 2 0.663342
TNNC1 troponin C type 1 (slow) 0.663342
MYH8 myosin, heavy chain 8, skeletal muscle, perinatal 0.663342
TNNT1 troponin T type 1 (skeletal, slow) 0.663342
MYH7 myosin, heavy chain 7, cardiac muscle, beta 0.663342
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 0.663342
SRCIN1 SRC kinase signaling inhibitor 1 0.663342
MYH1 myosin, heavy chain 1, skeletal muscle, adult 0.663342
EZR ezrin 0.663342
LLGL1 lethal giant larvae homolog 1 (Drosophila) 0.663342
ABLIM1 actin binding LIM protein 1 0.663342
ABLIM3 actin binding LIM protein family, member 3 0.663342
ABLIM2 actin binding LIM protein family, member 2 0.663342
TNNC2 troponin C type 2 (fast) 0.663342
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 0.663342
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 0.663342
MYO6 myosin VI 0.663342
MYH13 myosin, heavy chain 13, skeletal muscle 0.663342
CATIP ciliogenesis associated TTC17 interacting protein 0.663342
TTC17 tetratricopeptide repeat domain 17 0.663342
SEPT11 septin 11 0.663342
DENND2A DENN/MADD domain containing 2A 0.663342
GAS2L3 growth arrest-specific 2 like 3 0.663342
DST dystonin 0.663342
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.663342
MTSS1 metastasis suppressor 1 0.663342
DAAM1 dishevelled associated activator of morphogenesis 1 0.663342
ZYX zyxin 0.663342
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic 0.237908
TPM1 tropomyosin 1 (alpha) 0.237908
ACTL7B actin-like 7B 0.237908
LSP1 lymphocyte-specific protein 1 0.237908
MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle 0.237908
MYOT myotilin 0.237908
FSCN3 fascin actin-bundling protein 3, testicular 0.237908
FSCN2 fascin actin-bundling protein 2, retinal 0.237908
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 0.237908
ESPN espin 0.237908
ZNF185 zinc finger protein 185 (LIM domain) 0.237908
MYOM1 myomesin 1 0.237908
CORO1B coronin, actin binding protein, 1B 0.237908
BFSP1 beaded filament structural protein 1, filensin 0.237908
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) 0.237908
TARS threonyl-tRNA synthetase 0.237908
ALDOA aldolase A, fructose-bisphosphate 0.237908
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.237908
PARVA parvin, alpha 0.237908
MYO1B myosin IB 0.237908
SEPT12 septin 12 0.237908
CAPN2 calpain 2, (m/II) large subunit 0.237908
TPM2 tropomyosin 2 (beta) 0.237908
PALLD palladin, cytoskeletal associated protein 0.237908
CAPG capping protein (actin filament), gelsolin-like 0.237908
DBNL drebrin-like 0.237908
GAS2 growth arrest-specific 2 0.237908
MYH4 myosin, heavy chain 4, skeletal muscle 0.237908
MYH14 myosin, heavy chain 14, non-muscle 0.237908
HAP1 huntingtin-associated protein 1 0.237908
NEB nebulin 0.237908
AMPH amphiphysin 0.237908
ZNF74 zinc finger protein 74 0.237908
SH3PXD2B SH3 and PX domains 2B 0.237908
ZNF174 zinc finger protein 174 0.237908
AHNAK AHNAK nucleoprotein 0.237908
PDLIM5 PDZ and LIM domain 5 0.237908
IQGAP2 IQ motif containing GTPase activating protein 2 0.237908
PDLIM7 PDZ and LIM domain 7 (enigma) 0.237908
PDLIM2 PDZ and LIM domain 2 (mystique) 0.237908
IQGAP1 IQ motif containing GTPase activating protein 1 0.237908
CROCC ciliary rootlet coiled-coil, rootletin 0.237908
KALRN kalirin, RhoGEF kinase 0.237908
RHOQ ras homolog family member Q 0.237908
H1F0 H1 histone family, member 0 0.237908
BMF Bcl2 modifying factor 0.237908
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.237908
FGD4 FYVE, RhoGEF and PH domain containing 4 0.237908
RAI14 retinoic acid induced 14 0.237908
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle 0.237908
SEPT2 septin 2 0.237908
DSTN destrin (actin depolymerizing factor) 0.237908
VASP vasodilator-stimulated phosphoprotein 0.237908
WASF1 WAS protein family, member 1 0.237908
KPTN kaptin (actin binding protein) 0.237908
GSN gelsolin 0.237908
WASF2 WAS protein family, member 2 0.237908
WASL Wiskott-Aldrich syndrome-like 0.237908
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3 0.237908
TTN titin 0.237908
ADD1 adducin 1 (alpha) 0.237908
ADD2 adducin 2 (beta) 0.237908
EPB41 erythrocyte membrane protein band 4.1 0.237908
APC2 adenomatosis polyposis coli 2 0.237908
AIF1L allograft inflammatory factor 1-like 0.237908
LASP1 LIM and SH3 protein 1 0.237908
WIPF1 WAS/WASL interacting protein family, member 1 0.237908
FAM129B family with sequence similarity 129, member B 0.237908
MYBPC3 myosin binding protein C, cardiac 0.237908
MPRIP myosin phosphatase Rho interacting protein 0.237908
MYH11 myosin, heavy chain 11, smooth muscle 0.237908
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 0.237908
TWF1 twinfilin actin binding protein 1 0.237908
ACTR1A ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) 0.237908
ACTR1B ARP1 actin-related protein 1 homolog B, centractin beta (yeast) 0.237908
NCOA5 nuclear receptor coactivator 5 0.237908
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa 0.237908
IPP intracisternal A particle-promoted polypeptide 0.237908
CCDC53 coiled-coil domain containing 53 0.237908
APOB apolipoprotein B 0.237908
PHC3 polyhomeotic homolog 3 (Drosophila) 0.237908
RPA1 replication protein A1, 70kDa 0.237908
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 0.237908
VCAM1 vascular cell adhesion molecule 1 0.237908
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1 0.237908
CAPZB capping protein (actin filament) muscle Z-line, beta 0.237908
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 0.237908
PLEKHH2 pleckstrin homology domain containing, family H (with MyTH4 domain) member 2 0.237908
ACTN2 actinin, alpha 2 0.237908
SPTA1 spectrin, alpha, erythrocytic 1 0.237908
KLHL17 kelch-like family member 17 0.237908
NCAPG non-SMC condensin I complex, subunit G 0.237908
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.237908
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1 0.237908
FERMT3 fermitin family member 3 0.237908
SPTBN1 spectrin, beta, non-erythrocytic 1 0.237908
MARCKS myristoylated alanine-rich protein kinase C substrate 0.237908
FHL2 four and a half LIM domains 2 0.237908
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 0.237908
KIF9 kinesin family member 9 0.237908
STK38L serine/threonine kinase 38 like 0.237908
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 0.237908
ADAM8 ADAM metallopeptidase domain 8 0.237908
NPFFR2 neuropeptide FF receptor 2 0.237908
CTTNBP2NL CTTNBP2 N-terminal like 0.237908
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3 0.237908
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 0.237908
C14ORF166 chromosome 14 open reading frame 166 0.237908
DYNLL2 dynein, light chain, LC8-type 2 0.237908
SYNPO2 synaptopodin 2 0.237908
SCNN1D sodium channel, non voltage gated 1 delta subunit 0.237908
SYNPO synaptopodin 0.237908
BIN1 bridging integrator 1 0.237908
DCTN3 dynactin 3 (p22) 0.237908
VILL villin-like 0.237908
NOTCH3 notch 3 0.237908
NMT1 N-myristoyltransferase 1 0.237908
KNTC1 kinetochore associated 1 0.237908
AVIL advillin 0.237908
MYADM myeloid-associated differentiation marker 0.237908
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow 0.237908
SORBS1 sorbin and SH3 domain containing 1 0.237908
DPYSL3 dihydropyrimidinase-like 3 0.237908
GYS2 glycogen synthase 2 (liver) 0.237908
LRIF1 ligand dependent nuclear receptor interacting factor 1 0.237908
MYL2 myosin, light chain 2, regulatory, cardiac, slow 0.237908
SPTB spectrin, beta, erythrocytic 0.237908
STAG2 stromal antigen 2 0.237908
NFE2 nuclear factor, erythroid 2 0.237908
WAS Wiskott-Aldrich syndrome 0.237908
MYL9 myosin, light chain 9, regulatory 0.237908
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 0.237908
INTS6 integrator complex subunit 6 0.237908
MYL1 myosin, light chain 1, alkali; skeletal, fast 0.237908
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle 0.237908
SMTN smoothelin 0.237908
MYL5 myosin, light chain 5, regulatory 0.237908
PPP1R12A protein phosphatase 1, regulatory subunit 12A 0.237908
SORBS2 sorbin and SH3 domain containing 2 0.237908
FLNB filamin B, beta 0.237908
CALD1 caldesmon 1 0.237908
PPP1R12B protein phosphatase 1, regulatory subunit 12B 0.237908
KLHL20 kelch-like family member 20 0.237908
EPB41L2 erythrocyte membrane protein band 4.1-like 2 0.237908
ADAM17 ADAM metallopeptidase domain 17 0.237908
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.237908
USH1G Usher syndrome 1G (autosomal recessive) 0.098109
MYO5A myosin VA (heavy chain 12, myoxin) 0.098109
LRRC16A leucine rich repeat containing 16A 0.098109
RCSD1 RCSD domain containing 1 0.098109
CORO1C coronin, actin binding protein, 1C 0.098109
MYO16 myosin XVI 0.098109
MYO7B myosin VIIB 0.098109
FLNA filamin A, alpha 0.098109
CORO6 coronin 6 0.098109
MYO1G myosin IG 0.098109
ABRA actin binding Rho activating protein 0.098109
MYO3B myosin IIIB 0.098109
MYO5B myosin VB 0.098109
MYO5C myosin VC 0.098109
MYBPC1 myosin binding protein C, slow type 0.098109
MYH15 myosin, heavy chain 15 0.098109
MYL4 myosin, light chain 4, alkali; atrial, embryonic 0.098109
MYH7B myosin, heavy chain 7B, cardiac muscle, beta 0.098109
MYO1D myosin ID 0.098109
MYBPH myosin binding protein H 0.098109
TRPV4 transient receptor potential cation channel, subfamily V, member 4 0.098109
MYO19 myosin XIX 0.098109
MYBPC2 myosin binding protein C, fast type 0.098109
CORO2A coronin, actin binding protein, 2A 0.098109
MYO1H myosin IH 0.098109
HAX1 HCLS1 associated protein X-1 0.098109
MYO15A myosin XVA 0.098109
MYO10 myosin X 0.098109
MYOM2 myomesin 2 0.098109
JUP junction plakoglobin 0.098109
FKBP15 FK506 binding protein 15, 133kDa 0.03318
CAPZA3 capping protein (actin filament) muscle Z-line, alpha 3 0.03318
FHOD3 formin homology 2 domain containing 3 0.03318
CRYAB crystallin, alpha B 0.03318
SH2B2 SH2B adaptor protein 2 0.03318
FGR FGR proto-oncogene, Src family tyrosine kinase 0.03318
DCTN4 dynactin 4 (p62) 0.03318
DCTN6 dynactin 6 0.03318
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae) 0.03318
AIF1 allograft inflammatory factor 1 0.03318
STX1A syntaxin 1A (brain) 0.03318
MYLK3 myosin light chain kinase 3 0.03318
TRIM32 tripartite motif containing 32 0.03318
MYO15B myosin XVB 0.03318
SHROOM1 shroom family member 1 0.03318
SHROOM2 shroom family member 2 0.03318
FERMT2 fermitin family member 2 0.03318
SHROOM4 shroom family member 4 0.03318
RLTPR RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing 0.03318
ARC activity-regulated cytoskeleton-associated protein 0.03318
TMOD4 tropomodulin 4 (muscle) 0.03318
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.03318
TMOD3 tropomodulin 3 (ubiquitous) 0.03318
DCTN1 dynactin 1 0.03318
ACTN4 actinin, alpha 4 0.03318
VCL vinculin 0.03318
ARHGAP32 Rho GTPase activating protein 32 0.03318
ARHGAP35 Rho GTPase activating protein 35 0.03318
MYOZ2 myozenin 2 0.03318
BIN3 bridging integrator 3 0.03318
NF2 neurofibromin 2 (merlin) 0.03318
CGN cingulin 0.03318
MICALL2 MICAL-like 2 0.03318
VPS18 vacuolar protein sorting 18 homolog (S. cerevisiae) 0.03318
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric 0.03318
MYL12B myosin, light chain 12B, regulatory 0.03318
PDLIM3 PDZ and LIM domain 3 0.03318
TNNI1 troponin I type 1 (skeletal, slow) 0.03318
DFNB31 deafness, autosomal recessive 31 0.03318
MST1R macrophage stimulating 1 receptor 0.03318
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like 0.03318
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.03318
GABARAP GABA(A) receptor-associated protein 0.03318
TLN1 talin 1 0.03318
FERMT1 fermitin family member 1 0.03318
CIT citron rho-interacting serine/threonine kinase 0.03318
KAT2B K(lysine) acetyltransferase 2B 0.03318
MYRIP myosin VIIA and Rab interacting protein 0.03318
OPHN1 oligophrenin 1 0.03318
MSRB1 methionine sulfoxide reductase B1 0.03318
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 0.03318
FMN1 formin 1 0.03318
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 0.03318
MYOZ1 myozenin 1 0.03318
PPP1R9A protein phosphatase 1, regulatory subunit 9A 0.03318
PPP1R9B protein phosphatase 1, regulatory subunit 9B 0.03318
PKNOX2 PBX/knotted 1 homeobox 2 0.03318
CTNNA3 catenin (cadherin-associated protein), alpha 3 0.03318
CTNNA2 catenin (cadherin-associated protein), alpha 2 0.03318
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia) 0.03318
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.03318
MLPH melanophilin 0.03318
HDAC4 histone deacetylase 4 0.03318
GAS7 growth arrest-specific 7 0.03318
FHL3 four and a half LIM domains 3 0.03318
KNCN kinocilin 0.03318
RAB22A RAB22A, member RAS oncogene family 0.03318
FAM101B family with sequence similarity 101, member B 0.03318
RAB5A RAB5A, member RAS oncogene family 0.03318
LURAP1 leucine rich adaptor protein 1 0.03318
CFL1 cofilin 1 (non-muscle) 0.03318
ACTR10 actin-related protein 10 homolog (S. cerevisiae) 0.03318
ANKRD26 ankyrin repeat domain 26 0.03318
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular) 0.03318
VANGL2 VANGL planar cell polarity protein 2 0.03318
COBL cordon-bleu WH2 repeat protein 0.03318
ACTG1 actin gamma 1 0.03318
MED28 mediator complex subunit 28 0.03318
ENAH enabled homolog (Drosophila) 0.03318
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.03318
RINL Ras and Rab interactor-like 0.03318
MYO7A myosin VIIA 0.03318
STK17B serine/threonine kinase 17b 0.03318
CFL2 cofilin 2 (muscle) 0.03318
CGNL1 cingulin-like 1 0.03318