aconitine-6797 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the aconitine-6797 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AHNAK AHNAK nucleoprotein
AKAP6 A kinase (PRKA) anchor protein 6
ANKLE2 ankyrin repeat and LEM domain containing 2
BGN biglycan
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C1ORF68 chromosome 1 open reading frame 68
C2ORF27A chromosome 2 open reading frame 27A
CA4 carbonic anhydrase IV
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CALCB calcitonin-related polypeptide beta
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CEP162 centrosomal protein 162kDa
CLCN7 chloride channel, voltage-sensitive 7
CNTD2 cyclin N-terminal domain containing 2
COL11A2 collagen, type XI, alpha 2
COL6A1 collagen, type VI, alpha 1
COPZ2 coatomer protein complex, subunit zeta 2
DACH1 dachshund family transcription factor 1
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DUSP13 dual specificity phosphatase 13
EGFL7 EGF-like-domain, multiple 7
EPN1 epsin 1
FADS2 fatty acid desaturase 2
FAM155A family with sequence similarity 155, member A
FAM63B family with sequence similarity 63, member B
FANCE Fanconi anemia, complementation group E
FER1L4 fer-1-like family member 4, pseudogene (functional)
FGF18 fibroblast growth factor 18
FLJ22184
FN1 fibronectin 1
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GNAS GNAS complex locus
GSAP gamma-secretase activating protein
ICA1 islet cell autoantigen 1, 69kDa
IFI27 interferon, alpha-inducible protein 27
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
JAKMIP2 janus kinase and microtubule interacting protein 2
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KIAA0319L KIAA0319-like
KIAA0754 KIAA0754
LAMA4 laminin, alpha 4
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LRRN3 leucine rich repeat neuronal 3
LTB4R leukotriene B4 receptor
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAPK7 mitogen-activated protein kinase 7
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MARS methionyl-tRNA synthetase
MED16 mediator complex subunit 16
MKL1 megakaryoblastic leukemia (translocation) 1
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MUC1 mucin 1, cell surface associated
MUC6 mucin 6, oligomeric mucus/gel-forming
MYH14 myosin, heavy chain 14, non-muscle
MYL10 myosin, light chain 10, regulatory
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
NR2F1 nuclear receptor subfamily 2, group F, member 1
OSBPL10 oxysterol binding protein-like 10
PCDHA9 protocadherin alpha 9
PCDHGA1 protocadherin gamma subfamily A, 1
PCDHGA10 protocadherin gamma subfamily A, 10
PDLIM5 PDZ and LIM domain 5
PER3 period circadian clock 3
PGAP1 post-GPI attachment to proteins 1
PLAC4 placenta-specific 4
PLD3 phospholipase D family, member 3
PLIN2 perilipin 2
PLXND1 plexin D1
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
PSD4 pleckstrin and Sec7 domain containing 4
PTCRA pre T-cell antigen receptor alpha
RPH3A rabphilin 3A
RPL23AP53 ribosomal protein L23a pseudogene 53
RREB1 ras responsive element binding protein 1
RUNDC3B RUN domain containing 3B
SAP30 Sin3A-associated protein, 30kDa
SAYSD1 SAYSVFN motif domain containing 1
SERHL2 serine hydrolase-like 2
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SLCO3A1 solute carrier organic anion transporter family, member 3A1
SPAG6 sperm associated antigen 6
SPINK5 serine peptidase inhibitor, Kazal type 5
SPRR1A small proline-rich protein 1A
TAOK1 TAO kinase 1
TBX5 T-box 5
TJP3 tight junction protein 3
VPS13B vacuolar protein sorting 13 homolog B (yeast)
WDR1 WD repeat domain 1
XYLB xylulokinase homolog (H. influenzae)
YY1 YY1 transcription factor
ZNF350 zinc finger protein 350

decreased expression

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ACOT8 acyl-CoA thioesterase 8
ADGRG2 adhesion G protein-coupled receptor G2
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AGBL5 ATP/GTP binding protein-like 5
AKAP12 A kinase (PRKA) anchor protein 12
ARC activity-regulated cytoskeleton-associated protein
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ASPHD1 aspartate beta-hydroxylase domain containing 1
BCORL1 BCL6 corepressor-like 1
BPHL biphenyl hydrolase-like (serine hydrolase)
BRAF B-Raf proto-oncogene, serine/threonine kinase
C7ORF43 chromosome 7 open reading frame 43
CAPG capping protein (actin filament), gelsolin-like
CBR4 carbonyl reductase 4
CBX8 chromobox homolog 8
CCDC134 coiled-coil domain containing 134
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD79B CD79b molecule, immunoglobulin-associated beta
CD82 CD82 molecule
CDR2L cerebellar degeneration-related protein 2-like
CFD complement factor D (adipsin)
CGREF1 cell growth regulator with EF-hand domain 1
CNGB3 cyclic nucleotide gated channel beta 3
CORT cortistatin
CTSF cathepsin F
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DSCAM Down syndrome cell adhesion molecule
DSE dermatan sulfate epimerase
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
ELAVL3 ELAV like neuron-specific RNA binding protein 3
ETAA1 Ewing tumor-associated antigen 1
EXD3 exonuclease 3'-5' domain containing 3
F3 coagulation factor III (thromboplastin, tissue factor)
FAM118A family with sequence similarity 118, member A
FAM169A family with sequence similarity 169, member A
FAM188A family with sequence similarity 188, member A
FBRS fibrosin
FBXL15 F-box and leucine-rich repeat protein 15
FBXO22 F-box protein 22
FER fer (fps/fes related) tyrosine kinase
GAMT guanidinoacetate N-methyltransferase
GRAMD4 GRAM domain containing 4
GRB7 growth factor receptor-bound protein 7
HIST1H2AJ histone cluster 1, H2aj
IGFBP6 insulin-like growth factor binding protein 6
LARP6 La ribonucleoprotein domain family, member 6
LGALS4 lectin, galactoside-binding, soluble, 4
LONP2 lon peptidase 2, peroxisomal
LRRC61 leucine rich repeat containing 61
MAN2C1 mannosidase, alpha, class 2C, member 1
MAST3 microtubule associated serine/threonine kinase 3
MBTD1 mbt domain containing 1
MED15 mediator complex subunit 15
MED9 mediator complex subunit 9
METTL8 methyltransferase like 8
MNX1 motor neuron and pancreas homeobox 1
MYL5 myosin, light chain 5, regulatory
NDRG1 N-myc downstream regulated 1
NDRG4 NDRG family member 4
ONECUT2 one cut homeobox 2
OVGP1 oviductal glycoprotein 1, 120kDa
PACS1 phosphofurin acidic cluster sorting protein 1
PADI1 peptidyl arginine deiminase, type I
PCDHGB5 protocadherin gamma subfamily B, 5
PHC1 polyhomeotic homolog 1 (Drosophila)
PLD2 phospholipase D2
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLXNA3 plexin A3
POLL polymerase (DNA directed), lambda
POMT2 protein-O-mannosyltransferase 2
PRR14L proline rich 14-like
RAB27B RAB27B, member RAS oncogene family
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RGS2 regulator of G-protein signaling 2
RPGR retinitis pigmentosa GTPase regulator
RPL13P5 ribosomal protein L13 pseudogene 5
SALL2 spalt-like transcription factor 2
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC35F5 solute carrier family 35, member F5
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLIT2 slit homolog 2 (Drosophila)
SMR3A submaxillary gland androgen regulated protein 3A
SOX3 SRY (sex determining region Y)-box 3
SP1 Sp1 transcription factor
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SUN2 Sad1 and UNC84 domain containing 2
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TTBK2 tau tubulin kinase 2
TUBA3C tubulin, alpha 3c
USP27X ubiquitin specific peptidase 27, X-linked
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF141 zinc finger protein 141
ZNF35 zinc finger protein 35
ZNF442 zinc finger protein 442
ZNF480 zinc finger protein 480
ZNF770 zinc finger protein 770