acetylsalicylsalicylic acid-1377 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the acetylsalicylsalicylic acid-1377 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOX1 acyl-CoA oxidase 1, palmitoyl
ANKRD46 ankyrin repeat domain 46
APAF1 apoptotic peptidase activating factor 1
ASMTL acetylserotonin O-methyltransferase-like
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATAD2B ATPase family, AAA domain containing 2B
ATXN2 ataxin 2
AVL9 AVL9 homolog (S. cerevisiase)
BCAT1 branched chain amino-acid transaminase 1, cytosolic
BCL2A1 BCL2-related protein A1
BCL6 B-cell CLL/lymphoma 6
C12ORF29 chromosome 12 open reading frame 29
C2ORF68 chromosome 2 open reading frame 68
C5AR1 complement component 5a receptor 1
C9ORF156 chromosome 9 open reading frame 156
CBX6 chromobox homolog 6
CLIC4 chloride intracellular channel 4
DRG2 developmentally regulated GTP binding protein 2
DSCR3 Down syndrome critical region 3
DUS2 dihydrouridine synthase 2
ENG endoglin
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EVI5 ecotropic viral integration site 5
FASTK Fas-activated serine/threonine kinase
FUZ fuzzy planar cell polarity protein
GIMAP5 GTPase, IMAP family member 5
GLG1 golgi glycoprotein 1
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GRK6 G protein-coupled receptor kinase 6
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa
HNF1B HNF1 homeobox B
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IL6ST interleukin 6 signal transducer
ILF3 interleukin enhancer binding factor 3, 90kDa
ITSN1 intersectin 1 (SH3 domain protein)
KDM2A lysine (K)-specific demethylase 2A
KDM5A lysine (K)-specific demethylase 5A
KPNA6 karyopherin alpha 6 (importin alpha 7)
KRI1 KRI1 homolog (S. cerevisiae)
LDLR low density lipoprotein receptor
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAPKBP1 mitogen-activated protein kinase binding protein 1
MBD1 methyl-CpG binding domain protein 1
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MTMR6 myotubularin related protein 6
NAP1L1 nucleosome assembly protein 1-like 1
NBEAL2 neurobeachin-like 2
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4
PARG poly (ADP-ribose) glycohydrolase
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1
PIAS4 protein inhibitor of activated STAT, 4
PIDD1 p53-induced death domain protein 1
PLEC plectin
PNISR PNN-interacting serine/arginine-rich protein
PPP1R7 protein phosphatase 1, regulatory subunit 7
PTBP3 polypyrimidine tract binding protein 3
PTGES prostaglandin E synthase
RAB5C RAB5C, member RAS oncogene family
RASSF4 Ras association (RalGDS/AF-6) domain family member 4
RHOBTB3 Rho-related BTB domain containing 3
RRP1 ribosomal RNA processing 1
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SMG5 SMG5 nonsense mediated mRNA decay factor
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive)
SPIDR scaffolding protein involved in DNA repair
STAU2 staufen double-stranded RNA binding protein 2
SUGP1 SURP and G patch domain containing 1
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast)
TMEM165 transmembrane protein 165
TMEM97 transmembrane protein 97
TOX4 TOX high mobility group box family member 4
TPI1 triosephosphate isomerase 1
TPT1 tumor protein, translationally-controlled 1
TRABD TraB domain containing
TSG101 tumor susceptibility 101
TSPYL2 TSPY-like 2
UBE2J1 ubiquitin-conjugating enzyme E2, J1
UNC13B unc-13 homolog B (C. elegans)
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
VWA8 von Willebrand factor A domain containing 8
WASF1 WAS protein family, member 1
WDR1 WD repeat domain 1
WEE1 WEE1 G2 checkpoint kinase
WWC2 WW and C2 domain containing 2
YIPF2 Yip1 domain family, member 2
YIPF6 Yip1 domain family, member 6
ZGPAT zinc finger, CCCH-type with G patch domain
ZNF133 zinc finger protein 133
ZNF280D zinc finger protein 280D
ZNF426 zinc finger protein 426
ZNF451 zinc finger protein 451
ZNF580 zinc finger protein 580
ZSWIM8 zinc finger, SWIM-type containing 8

decreased expression

Symbol Name
AATK apoptosis-associated tyrosine kinase
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ABHD4 abhydrolase domain containing 4
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
APOC4 apolipoprotein C-IV
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARMC7 armadillo repeat containing 7
B3GNT1
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BCORL1 BCL6 corepressor-like 1
BTNL3 butyrophilin-like 3
C11ORF68 chromosome 11 open reading frame 68
CASZ1 castor zinc finger 1
CD248 CD248 molecule, endosialin
CD82 CD82 molecule
CHMP1A charged multivesicular body protein 1A
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPA2 carboxypeptidase A2 (pancreatic)
CRYBG3 beta-gamma crystallin domain containing 3
DAO D-amino-acid oxidase
DBF4B DBF4 zinc finger B
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DHRS7B dehydrogenase/reductase (SDR family) member 7B
DRAM1 DNA-damage regulated autophagy modulator 1
DSN1 DSN1, MIS12 kinetochore complex component
ELP3 elongator acetyltransferase complex subunit 3
ELSPBP1 epididymal sperm binding protein 1
EPX eosinophil peroxidase
FANCC Fanconi anemia, complementation group C
FRAT1 frequently rearranged in advanced T-cell lymphomas 1
GAB2 GRB2-associated binding protein 2
GJD2 gap junction protein, delta 2, 36kDa
GMEB1 glucocorticoid modulatory element binding protein 1
HDAC5 histone deacetylase 5
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIST3H2A histone cluster 3, H2a
HK1 hexokinase 1
IGKV1D-13 immunoglobulin kappa variable 1D-13
IGSF6 immunoglobulin superfamily, member 6
ILK integrin-linked kinase
INF2 inverted formin, FH2 and WH2 domain containing
IRF7 interferon regulatory factor 7
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KDM5C lysine (K)-specific demethylase 5C
KIFC1 kinesin family member C1
MAPK3 mitogen-activated protein kinase 3
MCC mutated in colorectal cancers
MFSD12 major facilitator superfamily domain containing 12
MMP2 matrix metallopeptidase 2
MON1B MON1 secretory trafficking family member B
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MRPL52 mitochondrial ribosomal protein L52
MTERF4 mitochondrial transcription termination factor 4
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
NR1D2 nuclear receptor subfamily 1, group D, member 2
NXPH3 neurexophilin 3
OPHN1 oligophrenin 1
OR10J1 olfactory receptor, family 10, subfamily J, member 1
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OVGP1 oviductal glycoprotein 1, 120kDa
PARM1 prostate androgen-regulated mucin-like protein 1
PCDHGB5 protocadherin gamma subfamily B, 5
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PEPD peptidase D
PIGR polymeric immunoglobulin receptor
PODNL1 podocan-like 1
PTOV1 prostate tumor overexpressed 1
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
RNF122 ring finger protein 122
RNF146 ring finger protein 146
RPL23AP32 ribosomal protein L23a pseudogene 32
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SH3GL1 SH3-domain GRB2-like 1
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SLN sarcolipin
SREBF1 sterol regulatory element binding transcription factor 1
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast)
TRAIP TRAF interacting protein
TRAPPC11 trafficking protein particle complex 11
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TSPAN32 tetraspanin 32
TXLNA taxilin alpha
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UBIAD1 UbiA prenyltransferase domain containing 1
WDR19 WD repeat domain 19
WFS1 Wolfram syndrome 1 (wolframin)
YY2 YY2 transcription factor
ZBTB48 zinc finger and BTB domain containing 48
ZIM2 zinc finger, imprinted 2
ZNF211 zinc finger protein 211
ZNF85 zinc finger protein 85
ZNHIT2 zinc finger, HIT-type containing 2