acetylsalicylic acid-6924 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the acetylsalicylic acid-6924 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AFAP1 actin filament associated protein 1
ALB albumin
ANKRD26 ankyrin repeat domain 26
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
APLP1 amyloid beta (A4) precursor-like protein 1
BCAM basal cell adhesion molecule (Lutheran blood group)
BCL9 B-cell CLL/lymphoma 9
BGN biglycan
C18ORF25 chromosome 18 open reading frame 25
C1QTNF3 C1q and tumor necrosis factor related protein 3
C21ORF91 chromosome 21 open reading frame 91
CADM4 cell adhesion molecule 4
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CASP5 caspase 5, apoptosis-related cysteine peptidase
CCNO cyclin O
CCPG1 cell cycle progression 1
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
CLEC4A C-type lectin domain family 4, member A
CMKLR1 chemerin chemokine-like receptor 1
COL9A3 collagen, type IX, alpha 3
CROCC ciliary rootlet coiled-coil, rootletin
CTBS chitobiase, di-N-acetyl-
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8
DCTN1 dynactin 1
DCX doublecortin
DMTN dematin actin binding protein
DOHH deoxyhypusine hydroxylase/monooxygenase
DRP2 dystrophin related protein 2
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EDDM3B epididymal protein 3B
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
F5 coagulation factor V (proaccelerin, labile factor)
FAM114A2 family with sequence similarity 114, member A2
FAM63A family with sequence similarity 63, member A
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GAB2 GRB2-associated binding protein 2
GFER growth factor, augmenter of liver regeneration
GPC3 glypican 3
HIST1H2AI histone cluster 1, H2ai
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
IDI2-AS1 IDI2 antisense RNA 1
IL22 interleukin 22
INHBA inhibin, beta A
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KDM7A lysine (K)-specific demethylase 7A
KLK3 kallikrein-related peptidase 3
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LMAN1 lectin, mannose-binding, 1
LOX lysyl oxidase
LRP5L low density lipoprotein receptor-related protein 5-like
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MEP1B meprin A, beta
MRPL41 mitochondrial ribosomal protein L41
MUC3A mucin 3A, cell surface associated
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle
MYO15B myosin XVB
NCAPH2 non-SMC condensin II complex, subunit H2
NOP16 NOP16 nucleolar protein
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PAOX polyamine oxidase (exo-N4-amino)
PLAT plasminogen activator, tissue
PON1 paraoxonase 1
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PRMT2 protein arginine methyltransferase 2
PSG9 pregnancy specific beta-1-glycoprotein 9
PVR poliovirus receptor
RBM12B-AS1 RBM12B antisense RNA 1
RGS10 regulator of G-protein signaling 10
RHBG Rh family, B glycoprotein (gene/pseudogene)
RLN1 relaxin 1
RPS4Y1 ribosomal protein S4, Y-linked 1
RYR1 ryanodine receptor 1 (skeletal)
SCUBE3 signal peptide, CUB domain, EGF-like 3
SECTM1 secreted and transmembrane 1
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SLC16A4 solute carrier family 16, member 4
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SORBS2 sorbin and SH3 domain containing 2
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
THBS1 thrombospondin 1
TRA T cell receptor alpha locus
TRIM25 tripartite motif containing 25
TRIM66 tripartite motif containing 66
TRIO trio Rho guanine nucleotide exchange factor
TSC22D4 TSC22 domain family, member 4
TWF1 twinfilin actin binding protein 1
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VIM vimentin
WIZ widely interspaced zinc finger motifs
ZNF571 zinc finger protein 571
ZSWIM8 zinc finger, SWIM-type containing 8

decreased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
AHDC1 AT hook, DNA binding motif, containing 1
ALPK1 alpha-kinase 1
AP1AR adaptor-related protein complex 1 associated regulatory protein
ARRB2 arrestin, beta 2
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
C2CD2 C2 calcium-dependent domain containing 2
CALCOCO1 calcium binding and coiled-coil domain 1
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCDC25 coiled-coil domain containing 25
CCNL2 cyclin L2
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CDKL3 cyclin-dependent kinase-like 3
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta
CFD complement factor D (adipsin)
CXORF56 chromosome X open reading frame 56
DNA2 DNA replication helicase/nuclease 2
DSCAM Down syndrome cell adhesion molecule
EDEM2 ER degradation enhancer, mannosidase alpha-like 2
EXOC3 exocyst complex component 3
FANCC Fanconi anemia, complementation group C
FICD FIC domain containing
FIP1L1 factor interacting with PAPOLA and CPSF1
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GFOD1 glucose-fructose oxidoreductase domain containing 1
GTPBP2 GTP binding protein 2
HCFC2 host cell factor C2
HEATR3 HEAT repeat containing 3
HIRA histone cell cycle regulator
HIST1H1D histone cluster 1, H1d
HIST1H2AJ histone cluster 1, H2aj
HIST1H2AM histone cluster 1, H2am
HIST1H3B histone cluster 1, H3b
IER3IP1 immediate early response 3 interacting protein 1
IFT88 intraflagellar transport 88
IL10RB interleukin 10 receptor, beta
KAT2A K(lysine) acetyltransferase 2A
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KIAA0894 KIAA0894 protein
KIAA0895 KIAA0895
KIF3A kinesin family member 3A
KLHL12 kelch-like family member 12
LRRC42 leucine rich repeat containing 42
LYRM9 LYR motif containing 9
MANBA mannosidase, beta A, lysosomal
MIS18BP1 MIS18 binding protein 1
MOCS3 molybdenum cofactor synthesis 3
MORC3 MORC family CW-type zinc finger 3
MPI mannose phosphate isomerase
MT1H metallothionein 1H
MTRF1 mitochondrial translational release factor 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYLIP myosin regulatory light chain interacting protein
NDRG1 N-myc downstream regulated 1
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NHEJ1 nonhomologous end-joining factor 1
NTHL1 nth endonuclease III-like 1 (E. coli)
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PAQR3 progestin and adipoQ receptor family member III
PARPBP PARP1 binding protein
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
POMZP3 POM121 and ZP3 fusion
PPAP2C phosphatidic acid phosphatase type 2C
RAB17 RAB17, member RAS oncogene family
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RBL1 retinoblastoma-like 1
RECQL4 RecQ protein-like 4
RIBC2 RIB43A domain with coiled-coils 2
RNF31 ring finger protein 31
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SARS2 seryl-tRNA synthetase 2, mitochondrial
SCYL2 SCY1-like 2 (S. cerevisiae)
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC35F6 solute carrier family 35, member F6
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1
SMAD7 SMAD family member 7
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
STX5 syntaxin 5
SYTL2 synaptotagmin-like 2
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TGDS TDP-glucose 4,6-dehydratase
THOP1 thimet oligopeptidase 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM254 transmembrane protein 254
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TRAPPC2 trafficking protein particle complex 2
VASH2 vasohibin 2
XKR8 XK, Kell blood group complex subunit-related family, member 8
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZBTB3 zinc finger and BTB domain containing 3
ZNF394 zinc finger protein 394
ZNF665 zinc finger protein 665
ZNF675 zinc finger protein 675