acetylsalicylic acid-6164 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the acetylsalicylic acid-6164 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTN2 actinin, alpha 2
ADAM22 ADAM metallopeptidase domain 22
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AGMAT agmatine ureohydrolase (agmatinase)
AIF1 allograft inflammatory factor 1
APOD apolipoprotein D
AQP7 aquaporin 7
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ATP13A2 ATPase type 13A2
BICD1 bicaudal D homolog 1 (Drosophila)
BTN2A2 butyrophilin, subfamily 2, member A2
C10ORF95 chromosome 10 open reading frame 95
C1ORF61 chromosome 1 open reading frame 61
C7ORF69 chromosome 7 open reading frame 69
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal)
CLDN17 claudin 17
CLEC1A C-type lectin domain family 1, member A
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
DDO D-aspartate oxidase
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila)
DSG2 desmoglein 2
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FAM13A family with sequence similarity 13, member A
FBN1 fibrillin 1
FGB fibrinogen beta chain
GAST gastrin
GFAP glial fibrillary acidic protein
GJA8 gap junction protein, alpha 8, 50kDa
GLRA3 glycine receptor, alpha 3
IL3RA interleukin 3 receptor, alpha (low affinity)
IQSEC1 IQ motif and Sec7 domain 1
IRF4 interferon regulatory factor 4
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KIF25-AS1 KIF25 antisense RNA 1
KLF5 Kruppel-like factor 5 (intestinal)
KLRAP1 killer cell lectin-like receptor subfamily A pseudogene 1
LAMB4 laminin, beta 4
LOC79999 uncharacterized LOC79999
LRRC75B leucine rich repeat containing 75B
LTK leukocyte receptor tyrosine kinase
MRC2 mannose receptor, C type 2
MT3 metallothionein 3
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MYO6 myosin VI
NCKAP1 NCK-associated protein 1
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
NES nestin
NMUR1 neuromedin U receptor 1
NNAT neuronatin
NPEPL1 aminopeptidase-like 1
NPFF neuropeptide FF-amide peptide precursor
NPTX2 neuronal pentraxin II
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR6A1 nuclear receptor subfamily 6, group A, member 1
NXPH3 neurexophilin 3
OPRL1 opiate receptor-like 1
OR2H2 olfactory receptor, family 2, subfamily H, member 2
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PCNXL2 pecanex-like 2 (Drosophila)
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PIP prolactin-induced protein
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLEKHS1 pleckstrin homology domain containing, family S member 1
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PSG9 pregnancy specific beta-1-glycoprotein 9
PTCRA pre T-cell antigen receptor alpha
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PVR poliovirus receptor
PXN paxillin
RAMP2 receptor (G protein-coupled) activity modifying protein 2
RDH5 retinol dehydrogenase 5 (11-cis/9-cis)
RGS12 regulator of G-protein signaling 12
RHAG Rh-associated glycoprotein
RPL10 ribosomal protein L10
SCN4A sodium channel, voltage gated, type IV alpha subunit
SELENBP1 selenium binding protein 1
SH3BP1 SH3-domain binding protein 1
SH3D21 SH3 domain containing 21
SHANK2 SH3 and multiple ankyrin repeat domains 2
SIX3 SIX homeobox 3
SLC46A3 solute carrier family 46, member 3
SNCG synuclein, gamma (breast cancer-specific protein 1)
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
STAP1 signal transducing adaptor family member 1
SYNDIG1 synapse differentiation inducing 1
SYNGR4 synaptogyrin 4
TAL1 T-cell acute lymphocytic leukemia 1
TLDC1 TBC/LysM-associated domain containing 1
TLN2 talin 2
TMEM53 transmembrane protein 53
TNNT2 troponin T type 2 (cardiac)
TP53I11 tumor protein p53 inducible protein 11
TRD T cell receptor delta locus
TRIM17 tripartite motif containing 17
TRPV5 transient receptor potential cation channel, subfamily V, member 5
ZBTB7A zinc finger and BTB domain containing 7A

decreased expression

Symbol Name
ACPP acid phosphatase, prostate
ADAM15 ADAM metallopeptidase domain 15
ARMCX5 armadillo repeat containing, X-linked 5
ARSB arylsulfatase B
ASAP1-IT1 ASAP1 intronic transcript 1
ASGR2 asialoglycoprotein receptor 2
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
BBS10 Bardet-Biedl syndrome 10
BHLHE41 basic helix-loop-helix family, member e41
BTBD3 BTB (POZ) domain containing 3
C17ORF80 chromosome 17 open reading frame 80
C19ORF40 chromosome 19 open reading frame 40
C9ORF3 chromosome 9 open reading frame 3
CCDC106 coiled-coil domain containing 106
CCL20 chemokine (C-C motif) ligand 20
CDK6 cyclin-dependent kinase 6
CHM choroideremia (Rab escort protein 1)
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CLSPN claspin
CPPED1 calcineurin-like phosphoesterase domain containing 1
CSF1R colony stimulating factor 1 receptor
CTSV cathepsin V
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14
ECM1 extracellular matrix protein 1
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ERAP2 endoplasmic reticulum aminopeptidase 2
ERCC4 excision repair cross-complementation group 4
ERN2 endoplasmic reticulum to nucleus signaling 2
FKBP14 FK506 binding protein 14, 22 kDa
FKBP5 FK506 binding protein 5
GINS4 GINS complex subunit 4 (Sld5 homolog)
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPR22 G protein-coupled receptor 22
GRWD1 glutamate-rich WD repeat containing 1
GSR glutathione reductase
GUSBP3 glucuronidase, beta pseudogene 3
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIRA histone cell cycle regulator
HIST1H2BI histone cluster 1, H2bi
HLA-DMA major histocompatibility complex, class II, DM alpha
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HPSE heparanase
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL18 interleukin 18
IREB2 iron-responsive element binding protein 2
KCTD20 potassium channel tetramerization domain containing 20
LIG4 ligase IV, DNA, ATP-dependent
MBNL3 muscleblind-like splicing regulator 3
METTL16 methyltransferase like 16
MSANTD2 Myb/SANT-like DNA-binding domain containing 2
MTMR12 myotubularin related protein 12
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MXD3 MAX dimerization protein 3
MYL5 myosin, light chain 5, regulatory
NDE1 nudE neurodevelopment protein 1
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PGM3 phosphoglucomutase 3
PHC1 polyhomeotic homolog 1 (Drosophila)
PITX2 paired-like homeodomain 2
PPIEL peptidylprolyl isomerase E-like pseudogene
PWAR5 Prader Willi/Angelman region RNA 5
QPCT glutaminyl-peptide cyclotransferase
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB23 RAB23, member RAS oncogene family
RETN resistin
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RIN2 Ras and Rab interactor 2
RNF170 ring finger protein 170
RNF25 ring finger protein 25
RPL23AP32 ribosomal protein L23a pseudogene 32
SALL2 spalt-like transcription factor 2
SOX12 SRY (sex determining region Y)-box 12
SUGP1 SURP and G patch domain containing 1
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYNC syncoilin, intermediate filament protein
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TCTN1 tectonic family member 1
TEP1 telomerase-associated protein 1
TET3 tet methylcytosine dioxygenase 3
TICAM1 toll-like receptor adaptor molecule 1
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TLR8 toll-like receptor 8
TMEM115 transmembrane protein 115
UNC119 unc-119 homolog (C. elegans)
UPK3A uroplakin 3A
USB1 U6 snRNA biogenesis 1
VN1R1 vomeronasal 1 receptor 1
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae)
XAF1 XIAP associated factor 1
ZDHHC11 zinc finger, DHHC-type containing 11
ZFYVE16 zinc finger, FYVE domain containing 16
ZNF197 zinc finger protein 197
ZNF652 zinc finger protein 652