acetylsalicylic acid-5201 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the acetylsalicylic acid-5201 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ADAM12 ADAM metallopeptidase domain 12
ADARB1 adenosine deaminase, RNA-specific, B1
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AIF1 allograft inflammatory factor 1
ALOXE3 arachidonate lipoxygenase 3
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APC adenomatous polyposis coli
ASPH aspartate beta-hydroxylase
BAHCC1 BAH domain and coiled-coil containing 1
BHMT2 betaine--homocysteine S-methyltransferase 2
BIN1 bridging integrator 1
C15ORF39 chromosome 15 open reading frame 39
C17ORF59 chromosome 17 open reading frame 59
C19ORF73 chromosome 19 open reading frame 73
C1ORF54 chromosome 1 open reading frame 54
C6ORF10 chromosome 6 open reading frame 10
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CD36 CD36 molecule (thrombospondin receptor)
CD6 CD6 molecule
CHN2 chimerin 2
CLCN7 chloride channel, voltage-sensitive 7
CORO7 coronin 7
COX4I1 cytochrome c oxidase subunit IV isoform 1
CRIP1 cysteine-rich protein 1 (intestinal)
CXCR4 chemokine (C-X-C motif) receptor 4
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DFNB31 deafness, autosomal recessive 31
DGKQ diacylglycerol kinase, theta 110kDa
DOK5 docking protein 5
DRD1 dopamine receptor D1
EFNB3 ephrin-B3
EIF5A2 eukaryotic translation initiation factor 5A2
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FGF12 fibroblast growth factor 12
FLOT1 flotillin 1
FLT4 fms-related tyrosine kinase 4
FRMD4B FERM domain containing 4B
FSCN3 fascin actin-bundling protein 3, testicular
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GNB5 guanine nucleotide binding protein (G protein), beta 5
GSPT1 G1 to S phase transition 1
GUK1 guanylate kinase 1
HIST1H3F histone cluster 1, H3f
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
ICOSLG inducible T-cell co-stimulator ligand
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
MED9 mediator complex subunit 9
MUL1 mitochondrial E3 ubiquitin protein ligase 1
N4BP1 NEDD4 binding protein 1
NF1 neurofibromin 1
NOTCH4 notch 4
NT5DC3 5'-nucleotidase domain containing 3
OLFM1 olfactomedin 1
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PER1 period circadian clock 1
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLAT plasminogen activator, tissue
PLK3 polo-like kinase 3
POFUT1 protein O-fucosyltransferase 1
PPP5C protein phosphatase 5, catalytic subunit
PRKCE protein kinase C, epsilon
PTRF polymerase I and transcript release factor
RPA4 replication protein A4, 30kDa
RTEL1 regulator of telomere elongation helicase 1
RUNX1 runt-related transcription factor 1
RUSC2 RUN and SH3 domain containing 2
S100A13 S100 calcium binding protein A13
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SFRP4 secreted frizzled-related protein 4
SH2D3A SH2 domain containing 3A
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SP100 SP100 nuclear antigen
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SRSF7 serine/arginine-rich splicing factor 7
STAG3L4 stromal antigen 3-like 4 (pseudogene)
SYNDIG1 synapse differentiation inducing 1
TLN2 talin 2
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TP53I11 tumor protein p53 inducible protein 11
TPMT thiopurine S-methyltransferase
TRAK1 trafficking protein, kinesin binding 1
TRIM2 tripartite motif containing 2
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
TSPAN9 tetraspanin 9
TTC9 tetratricopeptide repeat domain 9
TUBA3C tubulin, alpha 3c
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
WDTC1 WD and tetratricopeptide repeats 1
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
ZNF440 zinc finger protein 440
ZNF493 zinc finger protein 493
ZSWIM1 zinc finger, SWIM-type containing 1

decreased expression

Symbol Name
ABHD4 abhydrolase domain containing 4
ADAP1 ArfGAP with dual PH domains 1
ADCY6 adenylate cyclase 6
ANKFY1 ankyrin repeat and FYVE domain containing 1
AP4M1 adaptor-related protein complex 4, mu 1 subunit
APOD apolipoprotein D
ARPIN actin-related protein 2/3 complex inhibitor
ARRB2 arrestin, beta 2
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BMP4 bone morphogenetic protein 4
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
BTF3P12 basic transcription factor 3 pseudogene 12
CAPG capping protein (actin filament), gelsolin-like
CBX8 chromobox homolog 8
CCDC9 coiled-coil domain containing 9
CDK20 cyclin-dependent kinase 20
CENPO centromere protein O
CENPT centromere protein T
CEP170B centrosomal protein 170B
CES3 carboxylesterase 3
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CORT cortistatin
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DOCK1 dedicator of cytokinesis 1
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EFHD2 EF-hand domain family, member D2
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EXO5 exonuclease 5
F2R coagulation factor II (thrombin) receptor
FBRS fibrosin
FBXL15 F-box and leucine-rich repeat protein 15
FBXO31 F-box protein 31
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GCHFR GTP cyclohydrolase I feedback regulator
GLS2 glutaminase 2 (liver, mitochondrial)
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GNL1 guanine nucleotide binding protein-like 1
GRTP1 growth hormone regulated TBC protein 1
GSTTP1 glutathione S-transferase theta pseudogene 1
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HELZ helicase with zinc finger
HIST1H4D histone cluster 1, H4d
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
IGSF1 immunoglobulin superfamily, member 1
IL17RA interleukin 17 receptor A
INCENP inner centromere protein antigens 135/155kDa
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KIAA0894 KIAA0894 protein
KLF7 Kruppel-like factor 7 (ubiquitous)
KLK6 kallikrein-related peptidase 6
KREMEN2 kringle containing transmembrane protein 2
LAMA3 laminin, alpha 3
MDM4 MDM4, p53 regulator
MGC12488
MMP3 matrix metallopeptidase 3
MRPS18C mitochondrial ribosomal protein S18C
MTERF4 mitochondrial transcription termination factor 4
NIPAL2 NIPA-like domain containing 2
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PADI1 peptidyl arginine deiminase, type I
PCBP4 poly(rC) binding protein 4
PCDHA6 protocadherin alpha 6
PCSK7 proprotein convertase subtilisin/kexin type 7
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLEKHO1 pleckstrin homology domain containing, family O member 1
PLEKHS1 pleckstrin homology domain containing, family S member 1
PYCRL pyrroline-5-carboxylate reductase-like
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
SIX1 SIX homeobox 1
SLIT2 slit homolog 2 (Drosophila)
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SOX12 SRY (sex determining region Y)-box 12
SPHK1 sphingosine kinase 1
STRA6 stimulated by retinoic acid 6
SYTL2 synaptotagmin-like 2
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TCHH trichohyalin
TCTN2 tectonic family member 2
TOLLIP toll interacting protein
TRAF2 TNF receptor-associated factor 2
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TWSG1 twisted gastrulation BMP signaling modulator 1
USB1 U6 snRNA biogenesis 1
VASH2 vasohibin 2
VGF VGF nerve growth factor inducible
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDR19 WD repeat domain 19
ZBTB44 zinc finger and BTB domain containing 44
ZNF205 zinc finger protein 205
ZNF428 zinc finger protein 428
ZNF446 zinc finger protein 446
ZNF516 zinc finger protein 516
ZNF669 zinc finger protein 669