acetylsalicylic acid-2664 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the acetylsalicylic acid-2664 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
AHCYL1 adenosylhomocysteinase-like 1
AIM1L absent in melanoma 1-like
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
AMDHD2 amidohydrolase domain containing 2
ANG angiogenin, ribonuclease, RNase A family, 5
ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
AURKA aurora kinase A
BGLAP bone gamma-carboxyglutamate (gla) protein
BLZF1 basic leucine zipper nuclear factor 1
C4BPA complement component 4 binding protein, alpha
C4ORF19 chromosome 4 open reading frame 19
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CAT catalase
CCDC9 coiled-coil domain containing 9
CCT8 chaperonin containing TCP1, subunit 8 (theta)
CD300C CD300c molecule
CFP complement factor properdin
CNOT3 CCR4-NOT transcription complex, subunit 3
COPE coatomer protein complex, subunit epsilon
CREBBP CREB binding protein
CREM cAMP responsive element modulator
CUL7 cullin 7
DAPK2 death-associated protein kinase 2
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DIAPH2 diaphanous-related formin 2
FAM105A family with sequence similarity 105, member A
FBLN1 fibulin 1
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FFAR3 free fatty acid receptor 3
FHL1 four and a half LIM domains 1
FKRP fukutin related protein
GK3P glycerol kinase 3 pseudogene
GPR21 G protein-coupled receptor 21
GRAP GRB2-related adaptor protein
GSTTP1 glutathione S-transferase theta pseudogene 1
HIPK3 homeodomain interacting protein kinase 3
HLA-DOA major histocompatibility complex, class II, DO alpha
HNMT histamine N-methyltransferase
HOXA1 homeobox A1
IGL immunoglobulin lambda locus
IL11 interleukin 11
INF2 inverted formin, FH2 and WH2 domain containing
IPP intracisternal A particle-promoted polypeptide
KCTD20 potassium channel tetramerization domain containing 20
KRT86 keratin 86, type II
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
LOC730101 uncharacterized LOC730101
MAN1A1 mannosidase, alpha, class 1A, member 1
MMP3 matrix metallopeptidase 3
MRC2 mannose receptor, C type 2
MTUS1 microtubule associated tumor suppressor 1
NCOA2 nuclear receptor coactivator 2
NQO1 NAD(P)H dehydrogenase, quinone 1
NUMA1 nuclear mitotic apparatus protein 1
OR7C1 olfactory receptor, family 7, subfamily C, member 1
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDLIM5 PDZ and LIM domain 5
PGBD5 piggyBac transposable element derived 5
POU2F2 POU class 2 homeobox 2
PPARA peroxisome proliferator-activated receptor alpha
PRSS22 protease, serine, 22
PTPRK protein tyrosine phosphatase, receptor type, K
PXN paxillin
RANBP1 RAN binding protein 1
RASAL2 RAS protein activator like 2
RPL23AP32 ribosomal protein L23a pseudogene 32
RYR1 ryanodine receptor 1 (skeletal)
SAP30 Sin3A-associated protein, 30kDa
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SERINC5 serine incorporator 5
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SHOX2 short stature homeobox 2
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SMAD5 SMAD family member 5
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SPAG1 sperm associated antigen 1
SSTR4 somatostatin receptor 4
STK11 serine/threonine kinase 11
STON1 stonin 1
STX11 syntaxin 11
STYK1 serine/threonine/tyrosine kinase 1
SYNPO synaptopodin
TAS2R1 taste receptor, type 2, member 1
TEX40 testis expressed 40
TRIM25 tripartite motif containing 25
TRIM45 tripartite motif containing 45
TRPS1 trichorhinophalangeal syndrome I
TSPAN9 tetraspanin 9
UBR4 ubiquitin protein ligase E3 component n-recognin 4
USP6NL USP6 N-terminal like
VCX2 variable charge, X-linked 2
ZCCHC4 zinc finger, CCHC domain containing 4
ZNF362 zinc finger protein 362

decreased expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ADAM2 ADAM metallopeptidase domain 2
ADGB androglobin
AEN apoptosis enhancing nuclease
ALG12 ALG12, alpha-1,6-mannosyltransferase
BATF basic leucine zipper transcription factor, ATF-like
BRAF B-Raf proto-oncogene, serine/threonine kinase
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
C8A complement component 8, alpha polypeptide
CLCF1 cardiotrophin-like cytokine factor 1
CLCN2 chloride channel, voltage-sensitive 2
CLIP2 CAP-GLY domain containing linker protein 2
CNN1 calponin 1, basic, smooth muscle
CPTP ceramide-1-phosphate transfer protein
CRYGC crystallin, gamma C
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXORF56 chromosome X open reading frame 56
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DOK3 docking protein 3
DSPP dentin sialophosphoprotein
DTX2 deltex 2, E3 ubiquitin ligase
EPHB6 EPH receptor B6
ERO1LB ERO1-like beta (S. cerevisiae)
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FBRS fibrosin
FBXL2 F-box and leucine-rich repeat protein 2
FLT4 fms-related tyrosine kinase 4
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FRMPD1 FERM and PDZ domain containing 1
FZD4 frizzled class receptor 4
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GPR65 G protein-coupled receptor 65
GPR68 G protein-coupled receptor 68
HAMP hepcidin antimicrobial peptide
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BN histone cluster 1, H2bn
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HP haptoglobin
HPR haptoglobin-related protein
HRH2 histamine receptor H2
IL12RB1 interleukin 12 receptor, beta 1
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
KDM8 lysine (K)-specific demethylase 8
KIAA1456 KIAA1456
LIN7B lin-7 homolog B (C. elegans)
LINC00597 long intergenic non-protein coding RNA 597
LOC100287590 uncharacterized LOC100287590
LYPLA2P1 lysophospholipase II pseudogene 1
MAGEB2 melanoma antigen family B2
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MCPH1 microcephalin 1
MEGF8 multiple EGF-like-domains 8
MLPH melanophilin
MRPS18C mitochondrial ribosomal protein S18C
NACA2 nascent polypeptide-associated complex alpha subunit 2
NAG18 NAG18 mRNA
NARFL nuclear prelamin A recognition factor-like
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NLGN1 neuroligin 1
NPFFR1 neuropeptide FF receptor 1
NPIPB3 nuclear pore complex interacting protein family, member B3
NXF2 nuclear RNA export factor 2
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PKD2L2 polycystic kidney disease 2-like 2
PLA2G15 phospholipase A2, group XV
PLTP phospholipid transfer protein
PMP22 peripheral myelin protein 22
POLH polymerase (DNA directed), eta
POLL polymerase (DNA directed), lambda
POM121 POM121 transmembrane nucleoporin
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
PRF1 perforin 1 (pore forming protein)
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
PYGB phosphorylase, glycogen; brain
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RETN resistin
RPL13P5 ribosomal protein L13 pseudogene 5
SCAMP4 secretory carrier membrane protein 4
SCN10A sodium channel, voltage gated, type X alpha subunit
SIX3 SIX homeobox 3
SLC12A8 solute carrier family 12, member 8
SLC22A18 solute carrier family 22, member 18
SPATA1 spermatogenesis associated 1
SPATA2L spermatogenesis associated 2-like
SYTL2 synaptotagmin-like 2
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TIGD6 tigger transposable element derived 6
TMEM120B transmembrane protein 120B
TMEM212 transmembrane protein 212
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNS2 tensin 2
UPB1 ureidopropionase, beta
ZNF345 zinc finger protein 345
ZNF76 zinc finger protein 76