acetylsalicylic acid-1629 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the acetylsalicylic acid-1629 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AFAP1 actin filament associated protein 1
AFF4 AF4/FMR2 family, member 4
ALDH3B2 aldehyde dehydrogenase 3 family, member B2
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ATAD5 ATPase family, AAA domain containing 5
ATF3 activating transcription factor 3
BAHCC1 BAH domain and coiled-coil containing 1
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CENPJ centromere protein J
CENPO centromere protein O
CNPPD1 cyclin Pas1/PHO80 domain containing 1
CPNE7 copine VII
CRELD1 cysteine-rich with EGF-like domains 1
CTBS chitobiase, di-N-acetyl-
CYLD cylindromatosis (turban tumor syndrome)
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DMC1 DNA meiotic recombinase 1
DTNA dystrobrevin, alpha
E2F4 E2F transcription factor 4, p107/p130-binding
EMP3 epithelial membrane protein 3
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
ETAA1 Ewing tumor-associated antigen 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FAM174B family with sequence similarity 174, member B
FAS Fas cell surface death receptor
FBXO11 F-box protein 11
FILIP1L filamin A interacting protein 1-like
FLJ42627 uncharacterized LOC645644
FOSL1 FOS-like antigen 1
FSCN1 fascin actin-bundling protein 1
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPATCH3 G patch domain containing 3
GRIK5 glutamate receptor, ionotropic, kainate 5
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HIST1H1D histone cluster 1, H1d
HLA-B major histocompatibility complex, class I, B
HLA-F major histocompatibility complex, class I, F
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HN1L hematological and neurological expressed 1-like
HOMER3 homer scaffolding protein 3
HOXC10 homeobox C10
HOXD11 homeobox D11
IQCK IQ motif containing K
ITGB5 integrin, beta 5
KAT6B K(lysine) acetyltransferase 6B
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KIAA0754 KIAA0754
LMO2 LIM domain only 2 (rhombotin-like 1)
LRP6 low density lipoprotein receptor-related protein 6
LZTR1 leucine-zipper-like transcription regulator 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MAPK8 mitogen-activated protein kinase 8
MARK4 MAP/microtubule affinity-regulating kinase 4
MARS methionyl-tRNA synthetase
MAZ MYC-associated zinc finger protein (purine-binding transcription factor)
MID1 midline 1
MKLN1 muskelin 1, intracellular mediator containing kelch motifs
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
NDRG2 NDRG family member 2
NIPAL2 NIPA-like domain containing 2
NLRX1 NLR family member X1
NR2C1 nuclear receptor subfamily 2, group C, member 1
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PDPK1 3-phosphoinositide dependent protein kinase 1
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRKCI protein kinase C, iota
PTPN14 protein tyrosine phosphatase, non-receptor type 14
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RCAN1 regulator of calcineurin 1
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RIMS2 regulating synaptic membrane exocytosis 2
RNF39 ring finger protein 39
RPL35A ribosomal protein L35a
RPL7 ribosomal protein L7
SECTM1 secreted and transmembrane 1
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SRPR signal recognition particle receptor (docking protein)
SYNC syncoilin, intermediate filament protein
TADA2A transcriptional adaptor 2A
TCP11L1 t-complex 11, testis-specific-like 1
TGOLN2 trans-golgi network protein 2
TMOD1 tropomodulin 1
TRPV1 transient receptor potential cation channel, subfamily V, member 1
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
VAX2 ventral anterior homeobox 2
VGF VGF nerve growth factor inducible
ZER1 zyg-11 related, cell cycle regulator
ZNF783 zinc finger family member 783

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ACAD10 acyl-CoA dehydrogenase family, member 10
ADGRE5 adhesion G protein-coupled receptor E5
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ALPK1 alpha-kinase 1
ANKRD40 ankyrin repeat domain 40
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARL15 ADP-ribosylation factor-like 15
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BAHD1 bromo adjacent homology domain containing 1
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BCL2L2 BCL2-like 2
C16ORF59 chromosome 16 open reading frame 59
C4ORF29 chromosome 4 open reading frame 29
C5ORF45 chromosome 5 open reading frame 45
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CALCOCO1 calcium binding and coiled-coil domain 1
CAMTA2 calmodulin binding transcription activator 2
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCDC186 coiled-coil domain containing 186
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD302 CD302 molecule
CEP97 centrosomal protein 97kDa
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLASRP CLK4-associating serine/arginine rich protein
CLCN2 chloride channel, voltage-sensitive 2
CTC1 CTS telomere maintenance complex component 1
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DSE dermatan sulfate epimerase
EAF2 ELL associated factor 2
EFHD2 EF-hand domain family, member D2
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM118A family with sequence similarity 118, member A
FKBP14 FK506 binding protein 14, 22 kDa
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GINS4 GINS complex subunit 4 (Sld5 homolog)
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H2AJ histone cluster 1, H2aj
IPO13 importin 13
IRF6 interferon regulatory factor 6
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITPKB inositol-trisphosphate 3-kinase B
JADE3 jade family PHD finger 3
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MED9 mediator complex subunit 9
MYL5 myosin, light chain 5, regulatory
NBEAL2 neurobeachin-like 2
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NPFFR1 neuropeptide FF receptor 1
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PARG poly (ADP-ribose) glycohydrolase
PHACTR4 phosphatase and actin regulator 4
PLD2 phospholipase D2
POLR1B polymerase (RNA) I polypeptide B, 128kDa
PRMT7 protein arginine methyltransferase 7
RAB33B RAB33B, member RAS oncogene family
RCOR3 REST corepressor 3
RNF170 ring finger protein 170
RNF31 ring finger protein 31
SETD1A SET domain containing 1A
SETD6 SET domain containing 6
SETD8 SET domain containing (lysine methyltransferase) 8
SH2B3 SH2B adaptor protein 3
SH2D4A SH2 domain containing 4A
SKA1 spindle and kinetochore associated complex subunit 1
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
TCTN1 tectonic family member 1
THRAP3 thyroid hormone receptor associated protein 3
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM177 transmembrane protein 177
TMEM57 transmembrane protein 57
TMUB2 transmembrane and ubiquitin-like domain containing 2
TRIM16 tripartite motif containing 16
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like
UBQLN4 ubiquilin 4
UNKL unkempt family zinc finger-like
VASH1 vasohibin 1
VEGFC vascular endothelial growth factor C
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial
ZNF160 zinc finger protein 160
ZNF205 zinc finger protein 205
ZNF250 zinc finger protein 250
ZNF324 zinc finger protein 324
ZNF611 zinc finger protein 611
ZNF623 zinc finger protein 623
ZNF652 zinc finger protein 652
ZNF668 zinc finger protein 668
ZNF721 zinc finger protein 721
ZNF778 zinc finger protein 778
ZNF813 zinc finger protein 813