acetylsalicylic acid-1204 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the acetylsalicylic acid-1204 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ACSL5 acyl-CoA synthetase long-chain family member 5
ADGRF5 adhesion G protein-coupled receptor F5
AKAP7 A kinase (PRKA) anchor protein 7
AKAP8L A kinase (PRKA) anchor protein 8-like
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ALDOB aldolase B, fructose-bisphosphate
ARTN artemin
ATP13A2 ATPase type 13A2
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BCAS1 breast carcinoma amplified sequence 1
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BTBD7 BTB (POZ) domain containing 7
C19ORF60 chromosome 19 open reading frame 60
C7ORF43 chromosome 7 open reading frame 43
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCNJ cyclin J
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CHN2 chimerin 2
CNPPD1 cyclin Pas1/PHO80 domain containing 1
CREB3L1 cAMP responsive element binding protein 3-like 1
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DHODH dihydroorotate dehydrogenase (quinone)
DUSP1 dual specificity phosphatase 1
EXOC7 exocyst complex component 7
FABP3 fatty acid binding protein 3, muscle and heart
FGFR2 fibroblast growth factor receptor 2
GAS7 growth arrest-specific 7
GLP1R glucagon-like peptide 1 receptor
GMIP GEM interacting protein
GPR137 G protein-coupled receptor 137
GREB1L growth regulation by estrogen in breast cancer-like
GRTP1 growth hormone regulated TBC protein 1
HIST1H2BJ histone cluster 1, H2bj
HSDL2 hydroxysteroid dehydrogenase like 2
ICA1 islet cell autoantigen 1, 69kDa
IGHM immunoglobulin heavy constant mu
INO80B INO80 complex subunit B
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
KDM4C lysine (K)-specific demethylase 4C
KIAA0754 KIAA0754
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LRRK1 leucine-rich repeat kinase 1
MAPK14 mitogen-activated protein kinase 14
MORN1 MORN repeat containing 1
MPDZ multiple PDZ domain protein
NF1 neurofibromin 1
NPAS2 neuronal PAS domain protein 2
NPFFR1 neuropeptide FF receptor 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
PAIP2B poly(A) binding protein interacting protein 2B
PARD6A par-6 family cell polarity regulator alpha
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDLIM3 PDZ and LIM domain 3
PEX1 peroxisomal biogenesis factor 1
PILRA paired immunoglobin-like type 2 receptor alpha
PMFBP1 polyamine modulated factor 1 binding protein 1
POLG polymerase (DNA directed), gamma
PPP1R7 protein phosphatase 1, regulatory subunit 7
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTN pleiotrophin
RAB31 RAB31, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAB40B RAB40B, member RAS oncogene family
RARA retinoic acid receptor, alpha
RCN3 reticulocalbin 3, EF-hand calcium binding domain
REC8 REC8 meiotic recombination protein
RGS14 regulator of G-protein signaling 14
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RNF19B ring finger protein 19B
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCIN scinderin
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SP100 SP100 nuclear antigen
SPHK2 sphingosine kinase 2
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
TADA2A transcriptional adaptor 2A
TBC1D30 TBC1 domain family, member 30
THRB thyroid hormone receptor, beta
TMEM19 transmembrane protein 19
TMEM209 transmembrane protein 209
TMEM231 transmembrane protein 231
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TRIM25 tripartite motif containing 25
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TTLL3 tubulin tyrosine ligase-like family member 3
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
USB1 U6 snRNA biogenesis 1
USF2 upstream transcription factor 2, c-fos interacting
VGLL1 vestigial-like family member 1
WDR25 WD repeat domain 25
ZNF280B zinc finger protein 280B
ZNF778 zinc finger protein 778

decreased expression

Symbol Name
AATK apoptosis-associated tyrosine kinase
ABHD4 abhydrolase domain containing 4
AEN apoptosis enhancing nuclease
ANKEF1 ankyrin repeat and EF-hand domain containing 1
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ARID3B AT rich interactive domain 3B (BRIGHT-like)
BTBD2 BTB (POZ) domain containing 2
BTC betacellulin
C19ORF40 chromosome 19 open reading frame 40
C4ORF29 chromosome 4 open reading frame 29
CA11 carbonic anhydrase XI
CALCOCO1 calcium binding and coiled-coil domain 1
CDKL3 cyclin-dependent kinase-like 3
CENPQ centromere protein Q
COBL cordon-bleu WH2 repeat protein
CPEB1 cytoplasmic polyadenylation element binding protein 1
CPVL carboxypeptidase, vitellogenic-like
CRABP2 cellular retinoic acid binding protein 2
DCAF17 DDB1 and CUL4 associated factor 17
DEPTOR DEP domain containing MTOR-interacting protein
DNAAF2 dynein, axonemal, assembly factor 2
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
EAF2 ELL associated factor 2
EDC4 enhancer of mRNA decapping 4
EFNA3 ephrin-A3
ELOVL4 ELOVL fatty acid elongase 4
ERCC2 excision repair cross-complementation group 2
FAM160B2 family with sequence similarity 160, member B2
FAM50B family with sequence similarity 50, member B
FANCF Fanconi anemia, complementation group F
FBXL6 F-box and leucine-rich repeat protein 6
FCHSD2 FCH and double SH3 domains 2
FGF1 fibroblast growth factor 1 (acidic)
GBX2 gastrulation brain homeobox 2
GLDC glycine dehydrogenase (decarboxylating)
GMEB1 glucocorticoid modulatory element binding protein 1
GRAMD4 GRAM domain containing 4
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H2AM histone cluster 1, H2am
HIST2H2AA3 histone cluster 2, H2aa3
HOXA1 homeobox A1
HS1BP3 HCLS1 binding protein 3
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
IFNAR1 interferon (alpha, beta and omega) receptor 1
IL15RA interleukin 15 receptor, alpha
IL17RA interleukin 17 receptor A
ISYNA1 inositol-3-phosphate synthase 1
JMJD4 jumonji domain containing 4
KIAA0894 KIAA0894 protein
KIAA0895 KIAA0895
KLF7 Kruppel-like factor 7 (ubiquitous)
LPAR3 lysophosphatidic acid receptor 3
LRRC8E leucine rich repeat containing 8 family, member E
MAGEH1 melanoma antigen family H1
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MBIP MAP3K12 binding inhibitory protein 1
MCTP1 multiple C2 domains, transmembrane 1
MPP1 membrane protein, palmitoylated 1, 55kDa
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MTERF4 mitochondrial transcription termination factor 4
MTG1 mitochondrial ribosome-associated GTPase 1
MYLK myosin light chain kinase
NT5DC3 5'-nucleotidase domain containing 3
PGM1 phosphoglucomutase 1
PHC1 polyhomeotic homolog 1 (Drosophila)
PLEKHO2 pleckstrin homology domain containing, family O member 2
PTK6 protein tyrosine kinase 6
PVRL3 poliovirus receptor-related 3
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RGS17 regulator of G-protein signaling 17
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SCUBE3 signal peptide, CUB domain, EGF-like 3
SECISBP2 SECIS binding protein 2
SIPA1 signal-induced proliferation-associated 1
SLC22A18 solute carrier family 22, member 18
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SNHG20 small nucleolar RNA host gene 20
SOX12 SRY (sex determining region Y)-box 12
STX17 syntaxin 17
TMEM104 transmembrane protein 104
TOR4A torsin family 4, member A
TPCN1 two pore segment channel 1
TRAPPC6A trafficking protein particle complex 6A
UEVLD UEV and lactate/malate dehyrogenase domains
URM1 ubiquitin related modifier 1
USP18 ubiquitin specific peptidase 18
WDR18 WD repeat domain 18
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZNF230 zinc finger protein 230
ZNF232 zinc finger protein 232
ZNF552 zinc finger protein 552
ZNF629 zinc finger protein 629
ZNF787 zinc finger protein 787