acetylsalicylic acid-1145 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the acetylsalicylic acid-1145 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3
ACOX1 acyl-CoA oxidase 1, palmitoyl
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
APAF1 apoptotic peptidase activating factor 1
APLP2 amyloid beta (A4) precursor-like protein 2
APOH apolipoprotein H (beta-2-glycoprotein I)
ARHGAP1 Rho GTPase activating protein 1
ARMC9 armadillo repeat containing 9
BCL2L2 BCL2-like 2
C7ORF43 chromosome 7 open reading frame 43
CAPG capping protein (actin filament), gelsolin-like
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD300C CD300c molecule
CDC25C cell division cycle 25C
CDKN2A cyclin-dependent kinase inhibitor 2A
CLUAP1 clusterin associated protein 1
CNOT8 CCR4-NOT transcription complex, subunit 8
CNTN1 contactin 1
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
CPTP ceramide-1-phosphate transfer protein
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
CTNS cystinosin, lysosomal cystine transporter
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DRD2 dopamine receptor D2
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
ELAC1 elaC ribonuclease Z 1
ELF2 E74-like factor 2 (ets domain transcription factor)
EXOSC9 exosome component 9
FAM188A family with sequence similarity 188, member A
FAS Fas cell surface death receptor
FCF1 FCF1 rRNA-processing protein
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FGFR1 fibroblast growth factor receptor 1
FHL1 four and a half LIM domains 1
FMO4 flavin containing monooxygenase 4
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
GPR19 G protein-coupled receptor 19
GTPBP4 GTP binding protein 4
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL3RA interleukin 3 receptor, alpha (low affinity)
ITSN1 intersectin 1 (SH3 domain protein)
KIAA0753 KIAA0753
LAMP1 lysosomal-associated membrane protein 1
LARP4B La ribonucleoprotein domain family, member 4B
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LTBP3 latent transforming growth factor beta binding protein 3
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MCL1 myeloid cell leukemia 1
MDFIC MyoD family inhibitor domain containing
MED20 mediator complex subunit 20
MED31 mediator complex subunit 31
MKL1 megakaryoblastic leukemia (translocation) 1
MYOF myoferlin
NAIP NLR family, apoptosis inhibitory protein
NEURL1 neuralized E3 ubiquitin protein ligase 1
NRF1 nuclear respiratory factor 1
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PCNXL2 pecanex-like 2 (Drosophila)
PILRA paired immunoglobin-like type 2 receptor alpha
PLK3 polo-like kinase 3
PTGER4 prostaglandin E receptor 4 (subtype EP4)
REEP1 receptor accessory protein 1
REST RE1-silencing transcription factor
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RHOH ras homolog family member H
RPL23AP32 ribosomal protein L23a pseudogene 32
RPS9 ribosomal protein S9
RUNX1 runt-related transcription factor 1
SC5D sterol-C5-desaturase
SCARB1 scavenger receptor class B, member 1
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SLC16A4 solute carrier family 16, member 4
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SMA4 glucuronidase, beta pseudogene
SMCO4 single-pass membrane protein with coiled-coil domains 4
SMR3A submaxillary gland androgen regulated protein 3A
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
SOX12 SRY (sex determining region Y)-box 12
SPTAN1 spectrin, alpha, non-erythrocytic 1
STAT5B signal transducer and activator of transcription 5B
TLR1 toll-like receptor 1
TM2D1 TM2 domain containing 1
TMEM259 transmembrane protein 259
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
TNNT1 troponin T type 1 (skeletal, slow)
TOP3A topoisomerase (DNA) III alpha
TPD52 tumor protein D52
TRAFD1 TRAF-type zinc finger domain containing 1
TRAIP TRAF interacting protein
TRIM23 tripartite motif containing 23
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
WBP4 WW domain binding protein 4
ZBTB25 zinc finger and BTB domain containing 25
ZCCHC24 zinc finger, CCHC domain containing 24

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
AGO4 argonaute RISC catalytic component 4
AIM1 absent in melanoma 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALG3 ALG3, alpha-1,3- mannosyltransferase
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ARHGAP12 Rho GTPase activating protein 12
ARHGAP17 Rho GTPase activating protein 17
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ASAP1-IT1 ASAP1 intronic transcript 1
AURKB aurora kinase B
BAK1 BCL2-antagonist/killer 1
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1
BRD9 bromodomain containing 9
BRPF1 bromodomain and PHD finger containing, 1
C11ORF21 chromosome 11 open reading frame 21
C14ORF159 chromosome 14 open reading frame 159
C16ORF59 chromosome 16 open reading frame 59
C17ORF70 chromosome 17 open reading frame 70
C8ORF60 chromosome 8 open reading frame 60
CD1D CD1d molecule
CFAP44 cilia and flagella associated protein 44
CLSPN claspin
CLSTN1 calsyntenin 1
CORO7 coronin 7
CXCR2 chemokine (C-X-C motif) receptor 2
DENND1C DENN/MADD domain containing 1C
DGAT1 diacylglycerol O-acyltransferase 1
DVL1 dishevelled segment polarity protein 1
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
DYSF dysferlin
ELP6 elongator acetyltransferase complex subunit 6
ERCC8 excision repair cross-complementation group 8
ERN2 endoplasmic reticulum to nucleus signaling 2
ETV6 ets variant 6
FAM127A family with sequence similarity 127, member A
FAM50B family with sequence similarity 50, member B
FAM53B family with sequence similarity 53, member B
FAM86B1 family with sequence similarity 86, member B1
FBXL7 F-box and leucine-rich repeat protein 7
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FKBP5 FK506 binding protein 5
FOXN2 forkhead box N2
GOLGA3 golgin A3
GORASP1 golgi reassembly stacking protein 1, 65kDa
GUSBP3 glucuronidase, beta pseudogene 3
H1FX H1 histone family, member X
HIST1H1E histone cluster 1, H1e
IL4R interleukin 4 receptor
KIAA0754 KIAA0754
KIFAP3 kinesin-associated protein 3
LPAR4 lysophosphatidic acid receptor 4
LRRC42 leucine rich repeat containing 42
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MAST3 microtubule associated serine/threonine kinase 3
MED24 mediator complex subunit 24
MREG melanoregulin
MTERF1 mitochondrial transcription termination factor 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NAA40 N(alpha)-acetyltransferase 40, NatD catalytic subunit
NABP2 nucleic acid binding protein 2
NAT6 N-acetyltransferase 6 (GCN5-related)
NR1H2 nuclear receptor subfamily 1, group H, member 2
NTHL1 nth endonuclease III-like 1 (E. coli)
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PEPD peptidase D
PISD phosphatidylserine decarboxylase
PLTP phospholipid transfer protein
PTDSS2 phosphatidylserine synthase 2
QTRT1 queuine tRNA-ribosyltransferase 1
RAD54L2 RAD54-like 2 (S. cerevisiae)
RPA4 replication protein A4, 30kDa
RPAP1 RNA polymerase II associated protein 1
SEC31B SEC31 homolog B (S. cerevisiae)
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SHARPIN SHANK-associated RH domain interactor
SIPA1 signal-induced proliferation-associated 1
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SNHG20 small nucleolar RNA host gene 20
SPATA2L spermatogenesis associated 2-like
SREK1IP1 SREK1-interacting protein 1
TMEM104 transmembrane protein 104
TMEM254 transmembrane protein 254
TRDMT1 tRNA aspartic acid methyltransferase 1
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
TSPYL2 TSPY-like 2
TTC4 tetratricopeptide repeat domain 4
URM1 ubiquitin related modifier 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WASF3 WAS protein family, member 3
ZBTB48 zinc finger and BTB domain containing 48
ZC3H3 zinc finger CCCH-type containing 3
ZDHHC11 zinc finger, DHHC-type containing 11
ZDHHC18 zinc finger, DHHC-type containing 18
ZDHHC7 zinc finger, DHHC-type containing 7
ZNF10 zinc finger protein 10
ZNF747 zinc finger protein 747