acetylsalicylic acid-1042 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the acetylsalicylic acid-1042 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABI2 abl-interactor 2
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
ALPK1 alpha-kinase 1
ANXA11 annexin A11
ARG2 arginase 2
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ARRB1 arrestin, beta 1
ATP9A ATPase, class II, type 9A
C17ORF80 chromosome 17 open reading frame 80
C19ORF60 chromosome 19 open reading frame 60
C2CD2L C2CD2-like
CAMTA1 calmodulin binding transcription activator 1
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CDC14B cell division cycle 14B
CDK19 cyclin-dependent kinase 19
CGREF1 cell growth regulator with EF-hand domain 1
CIC capicua transcriptional repressor
COL5A1 collagen, type V, alpha 1
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2
CUEDC1 CUE domain containing 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DEPDC1 DEP domain containing 1
DIAPH2 diaphanous-related formin 2
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNMBP dynamin binding protein
DUSP1 dual specificity phosphatase 1
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
ERO1L ERO1-like (S. cerevisiae)
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GK glycerol kinase
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GOSR2 golgi SNAP receptor complex member 2
GRB10 growth factor receptor-bound protein 10
GSTM2 glutathione S-transferase mu 2 (muscle)
HFE hemochromatosis
HIST1H1C histone cluster 1, H1c
HIST1H2AI histone cluster 1, H2ai
ITFG2 integrin alpha FG-GAP repeat containing 2
JUN jun proto-oncogene
KCNK1 potassium channel, two pore domain subfamily K, member 1
KHK ketohexokinase (fructokinase)
KHSRP KH-type splicing regulatory protein
KLHL26 kelch-like family member 26
KRI1 KRI1 homolog (S. cerevisiae)
LDLR low density lipoprotein receptor
LONP2 lon peptidase 2, peroxisomal
LUC7L3 LUC7-like 3 (S. cerevisiae)
MAGEH1 melanoma antigen family H1
MANEA mannosidase, endo-alpha
MBIP MAP3K12 binding inhibitory protein 1
MED14 mediator complex subunit 14
MOSPD2 motile sperm domain containing 2
MSH3 mutS homolog 3
NAIP NLR family, apoptosis inhibitory protein
NEBL nebulette
NKIRAS2 NFKB inhibitor interacting Ras-like 2
OASL 2'-5'-oligoadenylate synthetase-like
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PIGO phosphatidylinositol glycan anchor biosynthesis, class O
PINK1 PTEN induced putative kinase 1
POLDIP3 polymerase (DNA-directed), delta interacting protein 3
PRR14L proline rich 14-like
PTPRA protein tyrosine phosphatase, receptor type, A
PVR poliovirus receptor
RAD51B RAD51 paralog B
RNF31 ring finger protein 31
RPGR retinitis pigmentosa GTPase regulator
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
SETD4 SET domain containing 4
SLC22A18 solute carrier family 22, member 18
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome)
SRSF8 serine/arginine-rich splicing factor 8
ST20 suppressor of tumorigenicity 20
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
STK3 serine/threonine kinase 3
SUGP1 SURP and G patch domain containing 1
TADA2A transcriptional adaptor 2A
TLDC1 TBC/LysM-associated domain containing 1
TMEM43 transmembrane protein 43
TMPRSS2 transmembrane protease, serine 2
TOP3A topoisomerase (DNA) III alpha
TRIM2 tripartite motif containing 2
TRIM23 tripartite motif containing 23
TRIM62 tripartite motif containing 62
UNC50 unc-50 homolog (C. elegans)
VWA8 von Willebrand factor A domain containing 8
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
ZBTB43 zinc finger and BTB domain containing 43
ZNF134 zinc finger protein 134
ZNF43 zinc finger protein 43
ZNF778 zinc finger protein 778
ZNF93 zinc finger protein 93
ZW10 zw10 kinetochore protein

decreased expression

Symbol Name
AAR2 AAR2 splicing factor homolog (S. cerevisiae)
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATF7IP2 activating transcription factor 7 interacting protein 2
BCAS4 breast carcinoma amplified sequence 4
C1ORF56 chromosome 1 open reading frame 56
C5 complement component 5
CARHSP1 calcium regulated heat stable protein 1, 24kDa
CBR1 carbonyl reductase 1
CBR4 carbonyl reductase 4
CBY1 chibby homolog 1 (Drosophila)
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CDT1 chromatin licensing and DNA replication factor 1
CENPJ centromere protein J
CINP cyclin-dependent kinase 2 interacting protein
CLASP1 cytoplasmic linker associated protein 1
CLK3 CDC-like kinase 3
CORO1A coronin, actin binding protein, 1A
DDB1 damage-specific DNA binding protein 1, 127kDa
DEXI Dexi homolog (mouse)
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DPF2 D4, zinc and double PHD fingers family 2
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FAM188A family with sequence similarity 188, member A
FAM206A family with sequence similarity 206, member A
FAM64A family with sequence similarity 64, member A
FOCAD focadhesin
HIST1H2BE histone cluster 1, H2be
HYAL2 hyaluronoglucosaminidase 2
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
JOSD1 Josephin domain containing 1
KIAA0232 KIAA0232
LYPD3 LY6/PLAUR domain containing 3
METTL16 methyltransferase like 16
MGMT O-6-methylguanine-DNA methyltransferase
MKS1 Meckel syndrome, type 1
MUS81 MUS81 structure-specific endonuclease subunit
NADSYN1 NAD synthetase 1
NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa
NR1D2 nuclear receptor subfamily 1, group D, member 2
OSGEP O-sialoglycoprotein endopeptidase
OSTF1 osteoclast stimulating factor 1
PANK4 pantothenate kinase 4
PAQR4 progestin and adipoQ receptor family member IV
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
PCSK7 proprotein convertase subtilisin/kexin type 7
PDZRN3 PDZ domain containing ring finger 3
PIEZO1 piezo-type mechanosensitive ion channel component 1
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
PISD phosphatidylserine decarboxylase
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLEKHO1 pleckstrin homology domain containing, family O member 1
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1
PYGB phosphorylase, glycogen; brain
RARS arginyl-tRNA synthetase
RBM23 RNA binding motif protein 23
RNF25 ring finger protein 25
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPS17P5 ribosomal protein S17 pseudogene 5
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
SARS2 seryl-tRNA synthetase 2, mitochondrial
SAV1 salvador family WW domain containing protein 1
SEC24B SEC24 family member B
SIRT7 sirtuin 7
SLC35A5 solute carrier family 35, member A5
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2
SS18L1 synovial sarcoma translocation gene on chromosome 18-like 1
SSFA2 sperm specific antigen 2
SYF2 SYF2 pre-mRNA-splicing factor
TBCCD1 TBCC domain containing 1
TCTN1 tectonic family member 1
TESK2 testis-specific kinase 2
THAP4 THAP domain containing 4
THUMPD2 THUMP domain containing 2
TIMP2 TIMP metallopeptidase inhibitor 2
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM115 transmembrane protein 115
TMEM39B transmembrane protein 39B
TMOD3 tropomodulin 3 (ubiquitous)
TSPO translocator protein (18kDa)
TWSG1 twisted gastrulation BMP signaling modulator 1
TXLNG taxilin gamma
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae)
XKR8 XK, Kell blood group complex subunit-related family, member 8
ZBTB5 zinc finger and BTB domain containing 5
ZMAT5 zinc finger, matrin-type 5
ZMYM3 zinc finger, MYM-type 3
ZNF266 zinc finger protein 266
ZNF273 zinc finger protein 273