acepromazine-6832 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the acepromazine-6832 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
AHNAK2 AHNAK nucleoprotein 2
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
ALDOB aldolase B, fructose-bisphosphate
APOE apolipoprotein E
APOM apolipoprotein M
ARTN artemin
ATP9A ATPase, class II, type 9A
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BAX BCL2-associated X protein
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide
C17ORF53 chromosome 17 open reading frame 53
CD3D CD3d molecule, delta (CD3-TCR complex)
CFAP69 cilia and flagella associated protein 69
COL4A1 collagen, type IV, alpha 1
CTNS cystinosin, lysosomal cystine transporter
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
DEFB126 defensin, beta 126
DNAI2 dynein, axonemal, intermediate chain 2
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DUSP4 dual specificity phosphatase 4
EHD2 EH-domain containing 2
EMCN endomucin
EXOSC1 exosome component 1
FBXL7 F-box and leucine-rich repeat protein 7
FBXO41 F-box protein 41
FGFBP1 fibroblast growth factor binding protein 1
FZD10 frizzled class receptor 10
GPR39 G protein-coupled receptor 39
GREB1 growth regulation by estrogen in breast cancer 1
HIST1H1E histone cluster 1, H1e
HIST1H4E histone cluster 1, H4e
HMOX1 heme oxygenase 1
HRH4 histamine receptor H4
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
IGSF6 immunoglobulin superfamily, member 6
IL11 interleukin 11
INPP5J inositol polyphosphate-5-phosphatase J
INSIG1 insulin induced gene 1
ITPK1 inositol-tetrakisphosphate 1-kinase
JUN jun proto-oncogene
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KLK7 kallikrein-related peptidase 7
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED16 mediator complex subunit 16
MEF2D myocyte enhancer factor 2D
MEG3 maternally expressed 3 (non-protein coding)
MID1 midline 1
MOCS1 molybdenum cofactor synthesis 1
MST1 macrophage stimulating 1
NCR2 natural cytotoxicity triggering receptor 2
NFIB nuclear factor I/B
NKX2-1 NK2 homeobox 1
NOD2 nucleotide-binding oligomerization domain containing 2
NOP16 NOP16 nucleolar protein
NOX1 NADPH oxidase 1
NT5M 5',3'-nucleotidase, mitochondrial
PBX2 pre-B-cell leukemia homeobox 2
PDCD6 programmed cell death 6
PDLIM5 PDZ and LIM domain 5
PEX16 peroxisomal biogenesis factor 16
PIP prolactin-induced protein
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRB1 proline-rich protein BstNI subfamily 1
PRR34 proline rich 34
PTAFR platelet-activating factor receptor
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTPN1 protein tyrosine phosphatase, non-receptor type 1
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RPL23AP32 ribosomal protein L23a pseudogene 32
SERGEF secretion regulating guanine nucleotide exchange factor
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SH2D2A SH2 domain containing 2A
SH3BP2 SH3-domain binding protein 2
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SLC35E2 solute carrier family 35, member E2
SOX12 SRY (sex determining region Y)-box 12
SRPK2 SRSF protein kinase 2
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1
TCP11L1 t-complex 11, testis-specific-like 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TMEM63A transmembrane protein 63A
TPSG1 tryptase gamma 1
VIPR1 vasoactive intestinal peptide receptor 1
ZCCHC24 zinc finger, CCHC domain containing 24
ZNF230 zinc finger protein 230
ZNF440 zinc finger protein 440
ZNF532 zinc finger protein 532
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ACSF2 acyl-CoA synthetase family member 2
ADAM15 ADAM metallopeptidase domain 15
ADCY6 adenylate cyclase 6
AHR aryl hydrocarbon receptor
ALPK1 alpha-kinase 1
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A
ANXA6 annexin A6
ARC activity-regulated cytoskeleton-associated protein
ARPIN actin-related protein 2/3 complex inhibitor
ARRB1 arrestin, beta 1
ATAD5 ATPase family, AAA domain containing 5
CARHSP1 calcium regulated heat stable protein 1, 24kDa
CBX8 chromobox homolog 8
CCDC15 coiled-coil domain containing 15
CCDC186 coiled-coil domain containing 186
CD82 CD82 molecule
CDK3 cyclin-dependent kinase 3
CEP72 centrosomal protein 72kDa
CSAD cysteine sulfinic acid decarboxylase
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DNA2 DNA replication helicase/nuclease 2
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7
DOC2A double C2-like domains, alpha
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EFNA3 ephrin-A3
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
ERCC4 excision repair cross-complementation group 4
ERN2 endoplasmic reticulum to nucleus signaling 2
FADD Fas (TNFRSF6)-associated via death domain
FBXO46 F-box protein 46
FBXW12 F-box and WD repeat domain containing 12
FGF23 fibroblast growth factor 23
GFOD1 glucose-fructose oxidoreductase domain containing 1
GINS4 GINS complex subunit 4 (Sld5 homolog)
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GUSBP3 glucuronidase, beta pseudogene 3
HDAC11 histone deacetylase 11
HLA-J major histocompatibility complex, class I, J (pseudogene)
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL17RA interleukin 17 receptor A
IP6K2 inositol hexakisphosphate kinase 2
IPP intracisternal A particle-promoted polypeptide
LHX6 LIM homeobox 6
LY6D lymphocyte antigen 6 complex, locus D
METRN meteorin, glial cell differentiation regulator
MVP major vault protein
NES nestin
NPFFR1 neuropeptide FF receptor 1
OSMR oncostatin M receptor
PADI3 peptidyl arginine deiminase, type III
PARP16 poly (ADP-ribose) polymerase family, member 16
PHACTR4 phosphatase and actin regulator 4
PHEX phosphate regulating endopeptidase homolog, X-linked
PODXL2 podocalyxin-like 2
POLR1B polymerase (RNA) I polypeptide B, 128kDa
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
POM121 POM121 transmembrane nucleoporin
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PPP5C protein phosphatase 5, catalytic subunit
PRR4 proline rich 4 (lacrimal)
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RBM41 RNA binding motif protein 41
RFWD3 ring finger and WD repeat domain 3
RHOBTB2 Rho-related BTB domain containing 2
RIN1 Ras and Rab interactor 1
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STEAP3 STEAP family member 3, metalloreductase
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAOK1 TAO kinase 1
TEP1 telomerase-associated protein 1
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TICAM1 toll-like receptor adaptor molecule 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
TUBA3C tubulin, alpha 3c
ULBP2 UL16 binding protein 2
VGF VGF nerve growth factor inducible
WDR46 WD repeat domain 46
WDR76 WD repeat domain 76
XK X-linked Kx blood group
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZNF160 zinc finger protein 160
ZNF276 zinc finger protein 276
ZNF611 zinc finger protein 611
ZNF652 zinc finger protein 652
ZNF721 zinc finger protein 721