acemetacin-6361 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the acemetacin-6361 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AATK apoptosis-associated tyrosine kinase
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ACOT11 acyl-CoA thioesterase 11
ACVR1B activin A receptor, type IB
AMT aminomethyltransferase
APOL6 apolipoprotein L, 6
ARHGAP24 Rho GTPase activating protein 24
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ATN1 atrophin 1
BAIAP3 BAI1-associated protein 3
BMP7 bone morphogenetic protein 7
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1
C17ORF53 chromosome 17 open reading frame 53
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CCNO cyclin O
CFAP45 cilia and flagella associated protein 45
CFLAR CASP8 and FADD-like apoptosis regulator
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CNR2 cannabinoid receptor 2 (macrophage)
COL11A2 collagen, type XI, alpha 2
COPE coatomer protein complex, subunit epsilon
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CTNND2 catenin (cadherin-associated protein), delta 2
CXCR6 chemokine (C-X-C motif) receptor 6
EFNB3 ephrin-B3
EMP1 epithelial membrane protein 1
ENPEP glutamyl aminopeptidase (aminopeptidase A)
ERAP1 endoplasmic reticulum aminopeptidase 1
ERC2-IT1 ERC2 intronic transcript 1
ESR1 estrogen receptor 1
FAM13A family with sequence similarity 13, member A
FASTKD2 FAST kinase domains 2
FGF1 fibroblast growth factor 1 (acidic)
GAL3ST4 galactose-3-O-sulfotransferase 4
GBP1 guanylate binding protein 1, interferon-inducible
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GP6 glycoprotein VI (platelet)
GPR137 G protein-coupled receptor 137
GPX2 glutathione peroxidase 2
HIC2 hypermethylated in cancer 2
HIST1H4D histone cluster 1, H4d
IFI44L interferon-induced protein 44-like
IFITM1 interferon induced transmembrane protein 1
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IGHM immunoglobulin heavy constant mu
IKZF5 IKAROS family zinc finger 5 (Pegasus)
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KAZN kazrin, periplakin interacting protein
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KDM4C lysine (K)-specific demethylase 4C
KRT34 keratin 34, type I
LDB1 LIM domain binding 1
LHFPL2 lipoma HMGIC fusion partner-like 2
MINK1 misshapen-like kinase 1
MTAP methylthioadenosine phosphorylase
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFRKB nuclear factor related to kappaB binding protein
NOX1 NADPH oxidase 1
NPTXR neuronal pentraxin receptor
NRCAM neuronal cell adhesion molecule
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
PABPN1 poly(A) binding protein, nuclear 1
PALM paralemmin
PDE4DIP phosphodiesterase 4D interacting protein
PLIN2 perilipin 2
PRDX2 peroxiredoxin 2
PRKCI protein kinase C, iota
RAB36 RAB36, member RAS oncogene family
RARG retinoic acid receptor, gamma
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF19B ring finger protein 19B
SCARA3 scavenger receptor class A, member 3
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SIDT2 SID1 transmembrane family, member 2
SLC48A1 solute carrier family 48 (heme transporter), member 1
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SRD5A3 steroid 5 alpha-reductase 3
STBD1 starch binding domain 1
STK16 serine/threonine kinase 16
STK17B serine/threonine kinase 17b
SYK spleen tyrosine kinase
TACC1 transforming, acidic coiled-coil containing protein 1
THBD thrombomodulin
TMEM63A transmembrane protein 63A
TOR1AIP1 torsin A interacting protein 1
TWISTNB TWIST neighbor
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UBE4B ubiquitination factor E4B
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
UNC119 unc-119 homolog (C. elegans)
USB1 U6 snRNA biogenesis 1
VWA1 von Willebrand factor A domain containing 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZBTB1 zinc finger and BTB domain containing 1
ZNF224 zinc finger protein 224
ZNF573 zinc finger protein 573
ZNF639 zinc finger protein 639

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADTRP androgen-dependent TFPI-regulating protein
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ANXA2P3 annexin A2 pseudogene 3
ASB6 ankyrin repeat and SOCS box containing 6
ATP10D ATPase, class V, type 10D
BAHD1 bromo adjacent homology domain containing 1
BAK1 BCL2-antagonist/killer 1
C17ORF70 chromosome 17 open reading frame 70
C17ORF80 chromosome 17 open reading frame 80
CCDC85C coiled-coil domain containing 85C
CDADC1 cytidine and dCMP deaminase domain containing 1
CDH3 cadherin 3, type 1, P-cadherin (placental)
CENPO centromere protein O
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CTC1 CTS telomere maintenance complex component 1
DAGLA diacylglycerol lipase, alpha
DDN dendrin
DEAF1 DEAF1 transcription factor
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DGKD diacylglycerol kinase, delta 130kDa
DOCK1 dedicator of cytokinesis 1
DYSF dysferlin
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EPPK1 epiplakin 1
ERF Ets2 repressor factor
EYA4 EYA transcriptional coactivator and phosphatase 4
FBXL7 F-box and leucine-rich repeat protein 7
FBXO2 F-box protein 2
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
GPC3 glypican 3
GPR39 G protein-coupled receptor 39
GTF2I general transcription factor IIi
HDAC5 histone deacetylase 5
HDAC7 histone deacetylase 7
HDAC9 histone deacetylase 9
HIRIP3 HIRA interacting protein 3
HIST1H2AI histone cluster 1, H2ai
HIST1H3G histone cluster 1, H3g
HLX H2.0-like homeobox
HOMER2 homer scaffolding protein 2
HOOK2 hook microtubule-tethering protein 2
HOXA6 homeobox A6
HOXC5 homeobox C5
ITPKB inositol-trisphosphate 3-kinase B
KLK6 kallikrein-related peptidase 6
LNPEP leucyl/cystinyl aminopeptidase
LPPR4 lipid phosphate phosphatase-related protein type 4
LYPLA2P1 lysophospholipase II pseudogene 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MBTPS2 membrane-bound transcription factor peptidase, site 2
MCOLN1 mucolipin 1
MGC12488
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTMR12 myotubularin related protein 12
MYBBP1A MYB binding protein (P160) 1a
MYOZ3 myozenin 3
NDRG4 NDRG family member 4
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NPY1R neuropeptide Y receptor Y1
NRTN neurturin
OLFML2A olfactomedin-like 2A
OPLAH 5-oxoprolinase (ATP-hydrolysing)
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PEX26 peroxisomal biogenesis factor 26
POLH polymerase (DNA directed), eta
POMT2 protein-O-mannosyltransferase 2
PRMT7 protein arginine methyltransferase 7
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RABL6 RAB, member RAS oncogene family-like 6
RIBC2 RIB43A domain with coiled-coils 2
RIN1 Ras and Rab interactor 1
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
S100A3 S100 calcium binding protein A3
SETBP1 SET binding protein 1
SH3GLB2 SH3-domain GRB2-like endophilin B2
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC46A3 solute carrier family 46, member 3
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
STIM1 stromal interaction molecule 1
SYNPO synaptopodin
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM110 transmembrane protein 110
TMEM242 transmembrane protein 242
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TRAIP TRAF interacting protein
TTLL7 tubulin tyrosine ligase-like family member 7
ZFHX3 zinc finger homeobox 3
ZFYVE16 zinc finger, FYVE domain containing 16
ZNF137P zinc finger protein 137, pseudogene
ZNF230 zinc finger protein 230
ZNF358 zinc finger protein 358