aceclofenac-7269 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the aceclofenac-7269 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
ACACA acetyl-CoA carboxylase alpha
AK1 adenylate kinase 1
AKAP9 A kinase (PRKA) anchor protein 9
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
AP3S2 adaptor-related protein complex 3, sigma 2 subunit
APC adenomatous polyposis coli
AVL9 AVL9 homolog (S. cerevisiase)
BBS7 Bardet-Biedl syndrome 7
BMP1 bone morphogenetic protein 1
BRWD1 bromodomain and WD repeat domain containing 1
C9ORF40 chromosome 9 open reading frame 40
CCL21 chemokine (C-C motif) ligand 21
CCL23 chemokine (C-C motif) ligand 23
CCL27 chemokine (C-C motif) ligand 27
CDC14A cell division cycle 14A
COL3A1 collagen, type III, alpha 1
CSNK1G2 casein kinase 1, gamma 2
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
CTNND2 catenin (cadherin-associated protein), delta 2
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DOCK5 dedicator of cytokinesis 5
DRD2 dopamine receptor D2
ELOVL4 ELOVL fatty acid elongase 4
EML3 echinoderm microtubule associated protein like 3
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EPN3 epsin 3
FKBP8 FK506 binding protein 8, 38kDa
FRMPD1 FERM and PDZ domain containing 1
FZD7 frizzled class receptor 7
GAS8 growth arrest-specific 8
GATA2 GATA binding protein 2
GLTSCR1 glioma tumor suppressor candidate region gene 1
GPR137 G protein-coupled receptor 137
GSN gelsolin
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IFIH1 interferon induced with helicase C domain 1
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL17RA interleukin 17 receptor A
KLK13 kallikrein-related peptidase 13
KRT19P2 keratin 19 pseudogene 2
L1CAM L1 cell adhesion molecule
LOC390998 ribosomal protein L10 pseudogene
LRRC41 leucine rich repeat containing 41
LY96 lymphocyte antigen 96
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MARK4 MAP/microtubule affinity-regulating kinase 4
MPZL1 myelin protein zero-like 1
MSL3 male-specific lethal 3 homolog (Drosophila)
MYH15 myosin, heavy chain 15
NCOR2 nuclear receptor corepressor 2
NOL12 nucleolar protein 12
NR4A2 nuclear receptor subfamily 4, group A, member 2
NUP214 nucleoporin 214kDa
PARVA parvin, alpha
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDE12 phosphodiesterase 12
PICK1 protein interacting with PRKCA 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PKD1 polycystic kidney disease 1 (autosomal dominant)
PLEKHO1 pleckstrin homology domain containing, family O member 1
PLXNA1 plexin A1
PRDM2 PR domain containing 2, with ZNF domain
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RGS10 regulator of G-protein signaling 10
RHEB Ras homolog enriched in brain
RNF19B ring finger protein 19B
SCAND2P SCAN domain containing 2 pseudogene
SERTAD3 SERTA domain containing 3
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SLC38A7 solute carrier family 38, member 7
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SMG7 SMG7 nonsense mediated mRNA decay factor
SOX13 SRY (sex determining region Y)-box 13
SPIDR scaffolding protein involved in DNA repair
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TBX10 T-box 10
THOC5 THO complex 5
TMEM2 transmembrane protein 2
TMEM231 transmembrane protein 231
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TRAFD1 TRAF-type zinc finger domain containing 1
TRIM23 tripartite motif containing 23
TSPAN2 tetraspanin 2
UBXN1 UBX domain protein 1
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
ZBTB1 zinc finger and BTB domain containing 1
ZNF224 zinc finger protein 224
ZNF442 zinc finger protein 442
ZNF768 zinc finger protein 768

decreased expression

Symbol Name
ABHD8 abhydrolase domain containing 8
AFAP1 actin filament associated protein 1
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
AMPD2 adenosine monophosphate deaminase 2
ANKFY1 ankyrin repeat and FYVE domain containing 1
ASB7 ankyrin repeat and SOCS box containing 7
BCAS4 breast carcinoma amplified sequence 4
C19ORF24 chromosome 19 open reading frame 24
C1ORF115 chromosome 1 open reading frame 115
C4ORF19 chromosome 4 open reading frame 19
C8ORF60 chromosome 8 open reading frame 60
CADPS2 Ca++-dependent secretion activator 2
CARD8 caspase recruitment domain family, member 8
CCDC88C coiled-coil domain containing 88C
CEMIP cell migration inducing protein, hyaluronan binding
CENPT centromere protein T
CEP131 centrosomal protein 131kDa
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7
CLASP1 cytoplasmic linker associated protein 1
COG4 component of oligomeric golgi complex 4
COQ6 coenzyme Q6 monooxygenase
CRIP1 cysteine-rich protein 1 (intestinal)
CTAGE9 CTAGE family, member 9
CTNNBL1 catenin, beta like 1
CXCL6 chemokine (C-X-C motif) ligand 6
DCLRE1A DNA cross-link repair 1A
DHRS11 dehydrogenase/reductase (SDR family) member 11
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DSE dermatan sulfate epimerase
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EN1 engrailed homeobox 1
ERN2 endoplasmic reticulum to nucleus signaling 2
ETV4 ets variant 4
FBXL14 F-box and leucine-rich repeat protein 14
FBXL4 F-box and leucine-rich repeat protein 4
FBXL6 F-box and leucine-rich repeat protein 6
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FDXR ferredoxin reductase
FXN frataxin
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GLCE glucuronic acid epimerase
GRPR gastrin-releasing peptide receptor
HMHA1 histocompatibility (minor) HA-1
HOXB13 homeobox B13
IL4R interleukin 4 receptor
IL7R interleukin 7 receptor
KIAA0753 KIAA0753
KIAA1551 KIAA1551
KIF20B kinesin family member 20B
KPTN kaptin (actin binding protein)
KRI1 KRI1 homolog (S. cerevisiae)
LRRC42 leucine rich repeat containing 42
LZTR1 leucine-zipper-like transcription regulator 1
MAP1S microtubule-associated protein 1S
MCRS1 microspherule protein 1
MUC3B mucin 3B, cell surface associated
MYLK myosin light chain kinase
NBEAL2 neurobeachin-like 2
NINJ1 ninjurin 1
NLK nemo-like kinase
NUPL2 nucleoporin like 2
ODF2 outer dense fiber of sperm tails 2
OLFML2A olfactomedin-like 2A
OSTF1 osteoclast stimulating factor 1
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
PAQR3 progestin and adipoQ receptor family member III
PC pyruvate carboxylase
PES1 pescadillo ribosomal biogenesis factor 1
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PTGES2 prostaglandin E synthase 2
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
RBM42 RNA binding motif protein 42
REV1 REV1, polymerase (DNA directed)
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SMYD5 SMYD family member 5
SNX17 sorting nexin 17
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STARD13 StAR-related lipid transfer (START) domain containing 13
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TM7SF2 transmembrane 7 superfamily member 2
TMEM104 transmembrane protein 104
TMEM209 transmembrane protein 209
TRABD TraB domain containing
UBTD1 ubiquitin domain containing 1
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
YIPF1 Yip1 domain family, member 1
ZBTB48 zinc finger and BTB domain containing 48
ZNF124 zinc finger protein 124
ZNF230 zinc finger protein 230
ZNF273 zinc finger protein 273
ZNF33B zinc finger protein 33B
ZNF629 zinc finger protein 629
ZNF816 zinc finger protein 816