aceclofenac-7029 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the aceclofenac-7029 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSM1 acyl-CoA synthetase medium-chain family member 1
ADCK2 aarF domain containing kinase 2
ADGRL1 adhesion G protein-coupled receptor L1
AHDC1 AT hook, DNA binding motif, containing 1
ALS2CL ALS2 C-terminal like
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15
ARMCX4 armadillo repeat containing, X-linked 4
ASTN2 astrotactin 2
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
ATXN2L ataxin 2-like
BCAT2 branched chain amino-acid transaminase 2, mitochondrial
BRD4 bromodomain containing 4
C2ORF68 chromosome 2 open reading frame 68
C9ORF9 chromosome 9 open reading frame 9
CA12 carbonic anhydrase XII
CAMTA1 calmodulin binding transcription activator 1
CC2D1A coiled-coil and C2 domain containing 1A
CCP110 centriolar coiled coil protein 110kDa
CDK3 cyclin-dependent kinase 3
CHD3 chromodomain helicase DNA binding protein 3
CLCN7 chloride channel, voltage-sensitive 7
CNR2 cannabinoid receptor 2 (macrophage)
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CREBZF CREB/ATF bZIP transcription factor
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CTSV cathepsin V
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DAGLA diacylglycerol lipase, alpha
DLC1 DLC1 Rho GTPase activating protein
DSTYK dual serine/threonine and tyrosine protein kinase
ELP6 elongator acetyltransferase complex subunit 6
FNBP1 formin binding protein 1
GLS2 glutaminase 2 (liver, mitochondrial)
GOSR2 golgi SNAP receptor complex member 2
GPC4 glypican 4
GPX2 glutathione peroxidase 2
GRK5 G protein-coupled receptor kinase 5
GSTTP1 glutathione S-transferase theta pseudogene 1
HDAC4 histone deacetylase 4
HOXA6 homeobox A6
IL1R2 interleukin 1 receptor, type II
IPO8 importin 8
JAKMIP2 janus kinase and microtubule interacting protein 2
JRK Jrk homolog (mouse)
KAT2A K(lysine) acetyltransferase 2A
KHNYN KH and NYN domain containing
KIAA0141 KIAA0141
KIAA0930 KIAA0930
KIF3C kinesin family member 3C
KLF11 Kruppel-like factor 11
LIG3 ligase III, DNA, ATP-dependent
LLGL1 lethal giant larvae homolog 1 (Drosophila)
MAP4 microtubule-associated protein 4
MARS methionyl-tRNA synthetase
MBD1 methyl-CpG binding domain protein 1
MEF2A myocyte enhancer factor 2A
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MTERF4 mitochondrial transcription termination factor 4
NDE1 nudE neurodevelopment protein 1
NF1 neurofibromin 1
NR5A2 nuclear receptor subfamily 5, group A, member 2
NRP1 neuropilin 1
NRSN2 neurensin 2
OGFRL1 opioid growth factor receptor-like 1
ONECUT2 one cut homeobox 2
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
OTUD3 OTU deubiquitinase 3
PDAP1 PDGFA associated protein 1
PDCD6 programmed cell death 6
PDE8B phosphodiesterase 8B
PDGFB platelet-derived growth factor beta polypeptide
PER3 period circadian clock 3
PHF20L1 PHD finger protein 20-like 1
PKNOX1 PBX/knotted 1 homeobox 1
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRDM2 PR domain containing 2, with ZNF domain
PSD4 pleckstrin and Sec7 domain containing 4
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RPL23AP32 ribosomal protein L23a pseudogene 32
SCLY selenocysteine lyase
SELL selectin L
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLC44A1 solute carrier family 44 (choline transporter), member 1
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
STAT5B signal transducer and activator of transcription 5B
STK17B serine/threonine kinase 17b
TCHH trichohyalin
TMEM254 transmembrane protein 254
TRIM36 tripartite motif containing 36
TRIM66 tripartite motif containing 66
XAB2 XPA binding protein 2
ZNF492 zinc finger protein 492
ZNF778 zinc finger protein 778
ZNF783 zinc finger family member 783
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ACVR2B activin A receptor, type IIB
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BBC3 BCL2 binding component 3
BCAS1 breast carcinoma amplified sequence 1
BEX4 brain expressed, X-linked 4
BTBD7 BTB (POZ) domain containing 7
CAPG capping protein (actin filament), gelsolin-like
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCDC130 coiled-coil domain containing 130
CCNO cyclin O
CHKB choline kinase beta
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CRABP1 cellular retinoic acid binding protein 1
CTH cystathionine gamma-lyase
CXORF56 chromosome X open reading frame 56
DCAF13 DDB1 and CUL4 associated factor 13
DDIT3 DNA-damage-inducible transcript 3
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DSCAM Down syndrome cell adhesion molecule
ECHDC2 enoyl CoA hydratase domain containing 2
EIF5A2 eukaryotic translation initiation factor 5A2
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative)
FADS3 fatty acid desaturase 3
FLT4 fms-related tyrosine kinase 4
FRAT1 frequently rearranged in advanced T-cell lymphomas 1
GATA6 GATA binding protein 6
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
HIST1H2AJ histone cluster 1, H2aj
IFT22 intraflagellar transport 22
IL15RA interleukin 15 receptor, alpha
IMPAD1 inositol monophosphatase domain containing 1
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
IQSEC2 IQ motif and Sec7 domain 2
KLF3 Kruppel-like factor 3 (basic)
LNPEP leucyl/cystinyl aminopeptidase
LOC390998 ribosomal protein L10 pseudogene
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LRRC49 leucine rich repeat containing 49
LY6D lymphocyte antigen 6 complex, locus D
LY6G5C lymphocyte antigen 6 complex, locus G5C
LYPD1 LY6/PLAUR domain containing 1
LYPLA2P1 lysophospholipase II pseudogene 1
MB myoglobin
MBTD1 mbt domain containing 1
MCRS1 microspherule protein 1
MED22 mediator complex subunit 22
MPI mannose phosphate isomerase
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
MRPL52 mitochondrial ribosomal protein L52
MSRA methionine sulfoxide reductase A
MTA2 metastasis associated 1 family, member 2
MTHFSD methenyltetrahydrofolate synthetase domain containing
NBEAL2 neurobeachin-like 2
NPY5R neuropeptide Y receptor Y5
PCDHA6 protocadherin alpha 6
PDLIM2 PDZ and LIM domain 2 (mystique)
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
POU2F1 POU class 2 homeobox 1
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
QTRT1 queuine tRNA-ribosyltransferase 1
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAB5C RAB5C, member RAS oncogene family
RABL3 RAB, member of RAS oncogene family-like 3
REM1 RAS (RAD and GEM)-like GTP-binding 1
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RIN2 Ras and Rab interactor 2
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF121 ring finger protein 121
RNF126P1 ring finger protein 126 pseudogene 1
SKA1 spindle and kinetochore associated complex subunit 1
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMG9 SMG9 nonsense mediated mRNA decay factor
SPRYD7 SPRY domain containing 7
SSBP3 single stranded DNA binding protein 3
STAG3 stromal antigen 3
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TICAM1 toll-like receptor adaptor molecule 1
TMEM104 transmembrane protein 104
TMEM212 transmembrane protein 212
TRIM25 tripartite motif containing 25
TRIM5 tripartite motif containing 5
TTLL1 tubulin tyrosine ligase-like family member 1
TUBA3C tubulin, alpha 3c
ULBP2 UL16 binding protein 2
VGF VGF nerve growth factor inducible
WFS1 Wolfram syndrome 1 (wolframin)
ZFP69B ZFP69 zinc finger protein B
ZNF668 zinc finger protein 668
ZNF767P zinc finger family member 767, pseudogene