aceclofenac-2281 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the aceclofenac-2281 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
AJAP1 adherens junctions associated protein 1
ANXA10 annexin A10
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ASPN asporin
BMP10 bone morphogenetic protein 10
CCDC64 coiled-coil domain containing 64
CDRT1 CMT1A duplicated region transcript 1
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CHD5 chromodomain helicase DNA binding protein 5
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLSTN3 calsyntenin 3
CLTC clathrin, heavy chain (Hc)
COL6A1 collagen, type VI, alpha 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DAAM2 dishevelled associated activator of morphogenesis 2
DCT dopachrome tautomerase
DMRT1 doublesex and mab-3 related transcription factor 1
DMXL2 Dmx-like 2
ERCC2 excision repair cross-complementation group 2
ETV5 ets variant 5
FAM63B family with sequence similarity 63, member B
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FHIT fragile histidine triad
GIPR gastric inhibitory polypeptide receptor
GM2A GM2 ganglioside activator
GPER1 G protein-coupled estrogen receptor 1
GPM6A glycoprotein M6A
GPR182 G protein-coupled receptor 182
GRIP2 glutamate receptor interacting protein 2
GUCY1B3 guanylate cyclase 1, soluble, beta 3
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HCFC1 host cell factor C1
HCRP1 hepatocellular carcinoma-related HCRP1
HIST1H2AK histone cluster 1, H2ak
HOXA10 homeobox A10
HUS1 HUS1 checkpoint homolog (S. pombe)
IKZF1 IKAROS family zinc finger 1 (Ikaros)
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KLF12 Kruppel-like factor 12
KLF9 Kruppel-like factor 9
KLHL25 kelch-like family member 25
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LAMC2 laminin, gamma 2
LGALS8 lectin, galactoside-binding, soluble, 8
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LMX1B LIM homeobox transcription factor 1, beta
LRRC6 leucine rich repeat containing 6
MAGEA5 melanoma antigen family A5
MAP4 microtubule-associated protein 4
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MEF2C myocyte enhancer factor 2C
MMP25 matrix metallopeptidase 25
MYL10 myosin, light chain 10, regulatory
MYO9B myosin IXB
N4BP2L1 NEDD4 binding protein 2-like 1
NEFM neurofilament, medium polypeptide
PADI1 peptidyl arginine deiminase, type I
PALM paralemmin
PCDH11X protocadherin 11 X-linked
PDIA2 protein disulfide isomerase family A, member 2
PDLIM4 PDZ and LIM domain 4
PDZRN4 PDZ domain containing ring finger 4
PGR progesterone receptor
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
POFUT1 protein O-fucosyltransferase 1
PON3 paraoxonase 3
PRDM1 PR domain containing 1, with ZNF domain
PRMT8 protein arginine methyltransferase 8
PRUNE2 prune homolog 2 (Drosophila)
PTAFR platelet-activating factor receptor
RASSF4 Ras association (RalGDS/AF-6) domain family member 4
RGS14 regulator of G-protein signaling 14
RHAG Rh-associated glycoprotein
RIMS2 regulating synaptic membrane exocytosis 2
RNF208 ring finger protein 208
RPS4Y1 ribosomal protein S4, Y-linked 1
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SIM2 single-minded family bHLH transcription factor 2
SIPA1L3 signal-induced proliferation-associated 1 like 3
SLC25A30 solute carrier family 25, member 30
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SNCG synuclein, gamma (breast cancer-specific protein 1)
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SSTR5 somatostatin receptor 5
TEF thyrotrophic embryonic factor
TEX15 testis expressed 15
TM4SF5 transmembrane 4 L six family member 5
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TPMT thiopurine S-methyltransferase
TUBA3C tubulin, alpha 3c
ZNF362 zinc finger protein 362
ZNF702P zinc finger protein 702, pseudogene

decreased expression

Symbol Name
ADAP2 ArfGAP with dual PH domains 2
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AHNAK2 AHNAK nucleoprotein 2
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BCL9 B-cell CLL/lymphoma 9
BFSP1 beaded filament structural protein 1, filensin
BHLHB9 basic helix-loop-helix domain containing, class B, 9
CBX8 chromobox homolog 8
CCDC25 coiled-coil domain containing 25
CCDC85C coiled-coil domain containing 85C
CES3 carboxylesterase 3
CLDN1 claudin 1
CLSTN2 calsyntenin 2
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DMTN dematin actin binding protein
DNAH17 dynein, axonemal, heavy chain 17
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DVL1 dishevelled segment polarity protein 1
EFCAB2 EF-hand calcium binding domain 2
ELP6 elongator acetyltransferase complex subunit 6
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ERN1 endoplasmic reticulum to nucleus signaling 1
ETV6 ets variant 6
EVPL envoplakin
EXO5 exonuclease 5
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FBXL2 F-box and leucine-rich repeat protein 2
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FGD1 FYVE, RhoGEF and PH domain containing 1
FLJ11710 uncharacterized protein FLJ11710
GADD45G growth arrest and DNA-damage-inducible, gamma
GATA4 GATA binding protein 4
GBP2 guanylate binding protein 2, interferon-inducible
GFI1 growth factor independent 1 transcription repressor
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GRTP1 growth hormone regulated TBC protein 1
HIST1H2AJ histone cluster 1, H2aj
HOXC4 homeobox C4
IQSEC2 IQ motif and Sec7 domain 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
KCNK12 potassium channel, two pore domain subfamily K, member 12
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KLHDC8A kelch domain containing 8A
LAMA3 laminin, alpha 3
LIME1 Lck interacting transmembrane adaptor 1
LTC4S leukotriene C4 synthase
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
LYPD1 LY6/PLAUR domain containing 1
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MAL mal, T-cell differentiation protein
MAP1S microtubule-associated protein 1S
MCOLN3 mucolipin 3
MTA2 metastasis associated 1 family, member 2
MUC3A mucin 3A, cell surface associated
NEUROD4 neuronal differentiation 4
NIPAL2 NIPA-like domain containing 2
NSD1 nuclear receptor binding SET domain protein 1
PAIP2B poly(A) binding protein interacting protein 2B
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLCD1 phospholipase C, delta 1
PPT2 palmitoyl-protein thioesterase 2
PRICKLE3 prickle homolog 3 (Drosophila)
RAB30 RAB30, member RAS oncogene family
RHOBTB2 Rho-related BTB domain containing 2
RNF122 ring finger protein 122
S100A9 S100 calcium binding protein A9
SCHIP1 schwannomin interacting protein 1
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SNTA1 syntrophin, alpha 1
SRD5A3 steroid 5 alpha-reductase 3
STON1 stonin 1
STX5 syntaxin 5
TARP TCR gamma alternate reading frame protein
TBC1D17 TBC1 domain family, member 17
TBC1D2 TBC1 domain family, member 2
TCTN1 tectonic family member 1
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TIGD6 tigger transposable element derived 6
TMC5 transmembrane channel-like 5
TMEM242 transmembrane protein 242
TPK1 thiamin pyrophosphokinase 1
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TSC22D4 TSC22 domain family, member 4
TTBK2 tau tubulin kinase 2
VGF VGF nerve growth factor inducible
WDR91 WD repeat domain 91
XDH xanthine dehydrogenase
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
YY2 YY2 transcription factor
ZBTB33 zinc finger and BTB domain containing 33
ZNF10 zinc finger protein 10
ZNF606 zinc finger protein 606