acacetin-4324 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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199 genes differentially expressed following the acacetin-4324 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ADCY2 adenylate cyclase 2 (brain)
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
AMPH amphiphysin
ANGPT1 angiopoietin 1
APOLD1 apolipoprotein L domain containing 1
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ASB13 ankyrin repeat and SOCS box containing 13
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BAIAP3 BAI1-associated protein 3
C1ORF95 chromosome 1 open reading frame 95
CA5B carbonic anhydrase VB, mitochondrial
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCDC132 coiled-coil domain containing 132
CCDC7 coiled-coil domain containing 7
CD34 CD34 molecule
CD52 CD52 molecule
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CREM cAMP responsive element modulator
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
CWH43 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae)
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DGCR8 DGCR8 microprocessor complex subunit
DIEXF digestive organ expansion factor homolog (zebrafish)
DMXL2 Dmx-like 2
DRD2 dopamine receptor D2
DTNB dystrobrevin, beta
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
EMC3 ER membrane protein complex subunit 3
FGF12 fibroblast growth factor 12
FKBP6 FK506 binding protein 6, 36kDa
FLOT1 flotillin 1
FOXF2 forkhead box F2
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1
HCAR3 hydroxycarboxylic acid receptor 3
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HRG histidine-rich glycoprotein
IGKV1D-13 immunoglobulin kappa variable 1D-13
ITGA7 integrin, alpha 7
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KLF6 Kruppel-like factor 6
KMT2A lysine (K)-specific methyltransferase 2A
KRT7 keratin 7, type II
LINC00216 long intergenic non-protein coding RNA 216
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LMNB1 lamin B1
LOC157562 uncharacterized LOC157562
LRRC17 leucine rich repeat containing 17
MCFD2 multiple coagulation factor deficiency 2
MED25 mediator complex subunit 25
MLXIP MLX interacting protein
MMP3 matrix metallopeptidase 3
MT1M metallothionein 1M
N4BP2L2 NEDD4 binding protein 2-like 2
NEK9 NIMA-related kinase 9
NT5M 5',3'-nucleotidase, mitochondrial
NUP54 nucleoporin 54kDa
ONECUT2 one cut homeobox 2
PCDHGA8 protocadherin gamma subfamily A, 8
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRB1 proline-rich protein BstNI subfamily 1
PRKG1 protein kinase, cGMP-dependent, type I
PROX1 prospero homeobox 1
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PVT1 Pvt1 oncogene (non-protein coding)
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
RAB40AL RAB40A, member RAS oncogene family-like
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1
REST RE1-silencing transcription factor
RIBC2 RIB43A domain with coiled-coils 2
RIMS1 regulating synaptic membrane exocytosis 1
RNF126P1 ring finger protein 126 pseudogene 1
RPL31 ribosomal protein L31
SAYSD1 SAYSVFN motif domain containing 1
SCNN1B sodium channel, non voltage gated 1 beta subunit
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SF1 splicing factor 1
SH3BP2 SH3-domain binding protein 2
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC4A5 solute carrier family 4 (sodium bicarbonate cotransporter), member 5
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SMG7 SMG7 nonsense mediated mRNA decay factor
SOX30 SRY (sex determining region Y)-box 30
SPPL2B signal peptide peptidase like 2B
TIMP4 TIMP metallopeptidase inhibitor 4
TPM3 tropomyosin 3
XYLB xylulokinase homolog (H. influenzae)
ZNF264 zinc finger protein 264
ZNF639 zinc finger protein 639
ZNF667 zinc finger protein 667

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ACTC1 actin, alpha, cardiac muscle 1
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
AHDC1 AT hook, DNA binding motif, containing 1
ALG12 ALG12, alpha-1,6-mannosyltransferase
AMT aminomethyltransferase
APLP1 amyloid beta (A4) precursor-like protein 1
ARID5B AT rich interactive domain 5B (MRF1-like)
ARL14 ADP-ribosylation factor-like 14
ASCC1 activating signal cointegrator 1 complex subunit 1
BIRC3 baculoviral IAP repeat containing 3
C1ORF54 chromosome 1 open reading frame 54
CA11 carbonic anhydrase XI
CBX8 chromobox homolog 8
CCDC106 coiled-coil domain containing 106
CCDC9 coiled-coil domain containing 9
CCNO cyclin O
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEMIP cell migration inducing protein, hyaluronan binding
CENPT centromere protein T
CHRDL1 chordin-like 1
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CLDN1 claudin 1
CLSPN claspin
CNOT3 CCR4-NOT transcription complex, subunit 3
CTGF connective tissue growth factor
DDIT3 DNA-damage-inducible transcript 3
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DLK2 delta-like 2 homolog (Drosophila)
DNM1 dynamin 1
EGR2 early growth response 2
ERN2 endoplasmic reticulum to nucleus signaling 2
EVPL envoplakin
EXOC6B exocyst complex component 6B
FA2H fatty acid 2-hydroxylase
FAM131B family with sequence similarity 131, member B
FHOD1 formin homology 2 domain containing 1
FOXD1 forkhead box D1
FSTL3 follistatin-like 3 (secreted glycoprotein)
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GREB1L growth regulation by estrogen in breast cancer-like
GSTM5 glutathione S-transferase mu 5
H1FX H1 histone family, member X
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H1T histone cluster 1, H1t
HIST1H3G histone cluster 1, H3g
HOXA4 homeobox A4
HOXC10 homeobox C10
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
HYAL3 hyaluronoglucosaminidase 3
IFNA17 interferon, alpha 17
JUNB jun B proto-oncogene
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
LIN7B lin-7 homolog B (C. elegans)
LMO7 LIM domain 7
LRRC61 leucine rich repeat containing 61
MAST4 microtubule associated serine/threonine kinase family member 4
MEPCE methylphosphate capping enzyme
MFGE8 milk fat globule-EGF factor 8 protein
MMP9 matrix metallopeptidase 9
MUC3B mucin 3B, cell surface associated
NKX3-2 NK3 homeobox 2
NTSR1 neurotensin receptor 1 (high affinity)
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PARP16 poly (ADP-ribose) polymerase family, member 16
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
POLL polymerase (DNA directed), lambda
PTPRU protein tyrosine phosphatase, receptor type, U
RNF2 ring finger protein 2
ROM1 retinal outer segment membrane protein 1
SCML2 sex comb on midleg-like 2 (Drosophila)
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SH3GL2 SH3-domain GRB2-like 2
SKA1 spindle and kinetochore associated complex subunit 1
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SLITRK5 SLIT and NTRK-like family, member 5
SMAD7 SMAD family member 7
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SSBP3 single stranded DNA binding protein 3
STRA6 stimulated by retinoic acid 6
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TGFBI transforming growth factor, beta-induced, 68kDa
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TLN1 talin 1
TOM1 target of myb1 (chicken)
TUBA3C tubulin, alpha 3c
TWIST1 twist family bHLH transcription factor 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VASH2 vasohibin 2
WBP2 WW domain binding protein 2
WT1-AS WT1 antisense RNA
ZC3H12A zinc finger CCCH-type containing 12A
ZNF165 zinc finger protein 165
ZNF215 zinc finger protein 215
ZNF248 zinc finger protein 248
ZNF446 zinc finger protein 446