acacetin-3767 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the acacetin-3767 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
AKR1C1 aldo-keto reductase family 1, member C1
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
AMPH amphiphysin
ANGPTL4 angiopoietin-like 4
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
ATHL1 ATH1, acid trehalase-like 1 (yeast)
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
BBC3 BCL2 binding component 3
BCAP29 B-cell receptor-associated protein 29
BLZF1 basic leucine zipper nuclear factor 1
C1QTNF3 C1q and tumor necrosis factor related protein 3
C2ORF27A chromosome 2 open reading frame 27A
C8B complement component 8, beta polypeptide
CASP10 caspase 10, apoptosis-related cysteine peptidase
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CD209 CD209 molecule
CD84 CD84 molecule
CEND1 cell cycle exit and neuronal differentiation 1
CHAT choline O-acetyltransferase
CHRNE cholinergic receptor, nicotinic, epsilon (muscle)
CIITA class II, major histocompatibility complex, transactivator
CLUAP1 clusterin associated protein 1
CREBZF CREB/ATF bZIP transcription factor
CRLF2 cytokine receptor-like factor 2
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DPF1 D4, zinc and double PHD fingers family 1
DRD5 dopamine receptor D5
DYM dymeclin
EGR1 early growth response 1
EPX eosinophil peroxidase
FBXO4 F-box protein 4
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FKBP10 FK506 binding protein 10, 65 kDa
FLJ11292
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FUBP1 far upstream element (FUSE) binding protein 1
GJA9 gap junction protein, alpha 9, 59kDa
GPR135 G protein-coupled receptor 135
GTPBP1 GTP binding protein 1
HLA-DOA major histocompatibility complex, class II, DO alpha
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
IFFO1 intermediate filament family orphan 1
IFNA16 interferon, alpha 16
IGLV4-60 immunoglobulin lambda variable 4-60
INSL4 insulin-like 4 (placenta)
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KIF25 kinesin family member 25
KLK13 kallikrein-related peptidase 13
LDLR low density lipoprotein receptor
LOC157562 uncharacterized LOC157562
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MFAP3L microfibrillar-associated protein 3-like
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MT1F metallothionein 1F
MT1M metallothionein 1M
N4BP2L2 NEDD4 binding protein 2-like 2
NDRG2 NDRG family member 2
NEK9 NIMA-related kinase 9
NOTCH3 notch 3
NPM3 nucleophosmin/nucleoplasmin 3
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OXCT2 3-oxoacid CoA transferase 2
PAQR6 progestin and adipoQ receptor family member VI
PBX2 pre-B-cell leukemia homeobox 2
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PRDM2 PR domain containing 2, with ZNF domain
PRKCI protein kinase C, iota
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
RAB30 RAB30, member RAS oncogene family
RDH5 retinol dehydrogenase 5 (11-cis/9-cis)
RPL10 ribosomal protein L10
RPL31 ribosomal protein L31
RPS4Y1 ribosomal protein S4, Y-linked 1
SENP5 SUMO1/sentrin specific peptidase 5
SH3BP2 SH3-domain binding protein 2
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SOX30 SRY (sex determining region Y)-box 30
SPTB spectrin, beta, erythrocytic
STAT2 signal transducer and activator of transcription 2, 113kDa
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TACC1 transforming, acidic coiled-coil containing protein 1
TAPBPL TAP binding protein-like
TESC tescalcin
TNPO2 transportin 2
TP53I11 tumor protein p53 inducible protein 11
TRIM3 tripartite motif containing 3
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae)
TSC22D2 TSC22 domain family, member 2
ZBTB1 zinc finger and BTB domain containing 1
ZBTB7A zinc finger and BTB domain containing 7A
ZIM2 zinc finger, imprinted 2
ZKSCAN1 zinc finger with KRAB and SCAN domains 1

decreased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADAP2 ArfGAP with dual PH domains 2
ADGRB2 adhesion G protein-coupled receptor B2
AGO4 argonaute RISC catalytic component 4
ARL14 ADP-ribosylation factor-like 14
BMP4 bone morphogenetic protein 4
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CCDC186 coiled-coil domain containing 186
CCDC85C coiled-coil domain containing 85C
CCNJL cyclin J-like
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CNTLN centlein, centrosomal protein
CNTNAP3B contactin associated protein-like 3B
CORO1A coronin, actin binding protein, 1A
CORO2B coronin, actin binding protein, 2B
CPZ carboxypeptidase Z
CRMP1 collapsin response mediator protein 1
CTGF connective tissue growth factor
CUTC cutC copper transporter
DCAF13 DDB1 and CUL4 associated factor 13
DDIT3 DNA-damage-inducible transcript 3
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DOCK1 dedicator of cytokinesis 1
EAF2 ELL associated factor 2
EHD3 EH-domain containing 3
EN2 engrailed homeobox 2
EPHA4 EPH receptor A4
ERF Ets2 repressor factor
FGF23 fibroblast growth factor 23
GALT galactose-1-phosphate uridylyltransferase
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
H1FX H1 histone family, member X
H2AFJ H2A histone family, member J
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HIST1H2BG histone cluster 1, H2bg
HOXA2 homeobox A2
HOXA4 homeobox A4
HOXA7 homeobox A7
HOXC13 homeobox C13
HSPA2 heat shock 70kDa protein 2
IFT81 intraflagellar transport 81
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KDM7A lysine (K)-specific demethylase 7A
KRT37 keratin 37, type I
KRT8P12 keratin 8 pseudogene 12
LMBR1L limb development membrane protein 1-like
MCOLN3 mucolipin 3
MLYCD malonyl-CoA decarboxylase
MOCS1 molybdenum cofactor synthesis 1
NEO1 neogenin 1
NINL ninein-like
NOL12 nucleolar protein 12
NT5M 5',3'-nucleotidase, mitochondrial
NTSR1 neurotensin receptor 1 (high affinity)
NUP62CL nucleoporin 62kDa C-terminal like
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PAQR5 progestin and adipoQ receptor family member V
PHACTR4 phosphatase and actin regulator 4
PICK1 protein interacting with PRKCA 1
PITX2 paired-like homeodomain 2
PLCD1 phospholipase C, delta 1
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
POLM polymerase (DNA directed), mu
PTPRU protein tyrosine phosphatase, receptor type, U
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF2 ring finger protein 2
RUNX1-IT1 RUNX1 intronic transcript 1
S100A3 S100 calcium binding protein A3
SAYSD1 SAYSVFN motif domain containing 1
SCEL sciellin
SCG2 secretogranin II
SCGB2A2 secretoglobin, family 2A, member 2
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMAD7 SMAD family member 7
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SRD5A3 steroid 5 alpha-reductase 3
TMC7 transmembrane channel-like 7
TMEM156 transmembrane protein 156
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TPK1 thiamin pyrophosphokinase 1
TRAIP TRAF interacting protein
TRIM25 tripartite motif containing 25
TSPAN32 tetraspanin 32
VASP vasodilator-stimulated phosphoprotein
WDR33 WD repeat domain 33
WDR62 WD repeat domain 62
YPEL1 yippee-like 1 (Drosophila)
ZNF573 zinc finger protein 573
ZNF586 zinc finger protein 586
ZNF701 zinc finger protein 701
ZNF711 zinc finger protein 711
ZNF747 zinc finger protein 747
ZNF768 zinc finger protein 768
ZNF778 zinc finger protein 778