absent type ii pneumocytes Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description absence of the granular and roughly cuboidal cells typically found at the alveolar-septal junction that modulate the fluid surrounding the alveolar epithelium by secreting and recycling surfactants, and also contribute to tissue repair and can differentiate after injury into a type I pneumocyte; type II cells cover a much smaller surface area than type I cells (less than 5 percent), but are much more numerous and contain lamellar bodies on the apical surface where surfactant is stored (Mammalian Phenotype Ontology, MP_0010812)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0010812
Similar Terms
Downloads & Tools

Genes

3 gene mutations causing the absent type ii pneumocytes phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
LYZ lysozyme
NKX2-1 NK2 homeobox 1
TCF21 transcription factor 21