absent spleen white pulp Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description absence of the parenchymatous tissue of the spleen that surrounds splenic blood vessels, consists of compact masses of lymphatic cells and is where foreign material removed from the blood is used to initiate an immune reaction that results in the production of antibodies (Mammalian Phenotype Ontology, MP_0005046)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0005046
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Genes

5 gene mutations causing the absent spleen white pulp phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
DCK deoxycytidine kinase
DIAPH1 diaphanous-related formin 1
IL2RG interleukin 2 receptor, gamma
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase