absent nk cells Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description absence of lymphocytes that can spontaneously kill a variety of target cells without prior antigenic activation via germline encoded activation receptors, and also regulate immune responses via cytokine release and direct contact with other cells (Mammalian Phenotype Ontology, MP_0008046)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008046
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Genes

6 gene mutations causing the absent nk cells phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL15 interleukin 15
IL2RG interleukin 2 receptor, gamma
IL6 interleukin 6
JAK3 Janus kinase 3