absent mature ovarian follicles Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description absence of ovarian follicles that are ready for ovulation and present a blanched spot (the follicular stigma) where the graafian follicle is about to rupture on the surface of the ovary; a first maturation (meiotic) division of the primary oocyte usually occurs just prior to rupture of the follicle (Mammalian Phenotype Ontology, MP_0001132)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0001132
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Genes

30 gene mutations causing the absent mature ovarian follicles phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
APC adenomatous polyposis coli
ARID5B AT rich interactive domain 5B (MRF1-like)
CGA glycoprotein hormones, alpha polypeptide
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
EGR1 early growth response 1
ESR1 estrogen receptor 1
FADS2 fatty acid desaturase 2
FOXL2 forkhead box L2
FSHB follicle stimulating hormone, beta polypeptide
FSHR follicle stimulating hormone receptor
FZD1 frizzled class receptor 1
GDF9 growth differentiation factor 9
GJA1 gap junction protein, alpha 1, 43kDa
HELQ helicase, POLQ-like
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
KISS1 KiSS-1 metastasis-suppressor
KISS1R KISS1 receptor
KL klotho
LHCGR luteinizing hormone/choriogonadotropin receptor
NPC1 Niemann-Pick disease, type C1
SLX4 SLX4 structure-specific endonuclease subunit
SPO11 SPO11 meiotic protein covalently bound to DSB
STRA8 stimulated by retinoic acid 8
SYCE3 synaptonemal complex central element protein 3
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TEX12 testis expressed 12
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VGF VGF nerve growth factor inducible
ZGLP1 zinc finger, GATA-like protein 1