absent b-1a cells Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description absence of the B-1 B cell subset bearing the CD5 surface marker (Mammalian Phenotype Ontology, MP_0008203)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008203
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Genes

7 gene mutations causing the absent b-1a cells phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
BLNK B-cell linker
BTK Bruton agammaglobulinemia tyrosine kinase
CARD11 caspase recruitment domain family, member 11
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
IKZF1 IKAROS family zinc finger 1 (Ikaros)
MALT1 MALT1 paracaspase
PIK3AP1 phosphoinositide-3-kinase adaptor protein 1