abnormal white fat cell morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of fat cells with light coloration and few mitochondria; these contain a scant ring of cytoplasm surrounding a single large lipid droplet or vacuole (Mammalian Phenotype Ontology, MP_0009117)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0009117
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Genes

58 gene mutations causing the abnormal white fat cell morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AGTR2 angiotensin II receptor, type 2
ARRDC3 arrestin domain containing 3
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
CAV1 caveolin 1, caveolae protein, 22kDa
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CES1 carboxylesterase 1
CNOT3 CCR4-NOT transcription complex, subunit 3
CRHR2 corticotropin releasing hormone receptor 2
CRTC3 CREB regulated transcription coactivator 3
CSPG4 chondroitin sulfate proteoglycan 4
EPG5 ectopic P-granules autophagy protein 5 homolog (C. elegans)
ESR1 estrogen receptor 1
ESRRA estrogen-related receptor alpha
FFAR4 free fatty acid receptor 4
FGF21 fibroblast growth factor 21
FGL1 fibrinogen-like 1
FTO fat mass and obesity associated
HDC histidine decarboxylase
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
INSIG1 insulin induced gene 1
KDM3A lysine (K)-specific demethylase 3A
KSR1 kinase suppressor of ras 1
LCLAT1 lysocardiolipin acyltransferase 1
LEP leptin
LGALS12 lectin, galactoside-binding, soluble, 12
LIPA lipase A, lysosomal acid, cholesterol esterase
LIPE lipase, hormone-sensitive
LPIN1 lipin 1
MC3R melanocortin 3 receptor
MFSD2A major facilitator superfamily domain containing 2A
MIR378A microRNA 378a
MRAP2 melanocortin 2 receptor accessory protein 2
NCOA3 nuclear receptor coactivator 3
NCOR1 nuclear receptor corepressor 1
NCOR2 nuclear receptor corepressor 2
NOS3 nitric oxide synthase 3 (endothelial cell)
NR1H4 nuclear receptor subfamily 1, group H, member 4
NR2C2 nuclear receptor subfamily 2, group C, member 2
OMA1 OMA1 zinc metallopeptidase
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PCNA proliferating cell nuclear antigen
PHF2 PHD finger protein 2
PLIN1 perilipin 1
PLIN2 perilipin 2
PLSCR3 phospholipid scramblase 3
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RBL1 retinoblastoma-like 1
SAMD4A sterile alpha motif domain containing 4A
SERTAD2 SERTA domain containing 2
SRA1 steroid receptor RNA activator 1
TBC1D4 TBC1 domain family, member 4
TGFB1 transforming growth factor, beta 1
TLR2 toll-like receptor 2
TRIB1 tribbles pseudokinase 1