abnormal vitamin a metabolism Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description altered ability to metabolize any of the vitamin A compounds, retinol, retinal (retinaldehyde) and retinoic acid; animals can not synthesize vitamin A de novo, but form it through oxidative cleavage of carotenoids supplied in the diet (Mammalian Phenotype Ontology, MP_0011233)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0011233
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Genes

11 gene mutations causing the abnormal vitamin a metabolism phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
DHRS3 dehydrogenase/reductase (SDR family) member 3
LRAT lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
PLIN2 perilipin 2
RBP1 retinol binding protein 1, cellular
RDH10 retinol dehydrogenase 10 (all-trans)
RPE65 retinal pigment epithelium-specific protein 65kDa
STRA6 stimulated by retinoic acid 6
TTR transthyretin