abnormal type iii hypersensitivity reaction Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description anomaly in the tissue injury mediated by immune complexes; generally involves immune complexes formed in the blood via Abs encountering circulating Ag-Ab complexes then deposit in tissues (especially blood vessels and glomeruli), induce complement activation, and result in tissue injury (Mammalian Phenotype Ontology, MP_0002533)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0002533
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Genes

5 gene mutations causing the abnormal type iii hypersensitivity reaction phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CCL3L3 chemokine (C-C motif) ligand 3-like 3
CCR1 chemokine (C-C motif) receptor 1
CFH complement factor H
FAS Fas cell surface death receptor
IKZF3 IKAROS family zinc finger 3 (Aiolos)