abnormal thymocyte activation Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description anomaly in the process of producing activated thymocytes from naive thymocytes (Mammalian Phenotype Ontology, MP_0003850)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0003850
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Genes

20 gene mutations causing the abnormal thymocyte activation phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CD247 CD247 molecule
CDK6 cyclin-dependent kinase 6
CORO1A coronin, actin binding protein, 1A
DTX1 deltex 1, E3 ubiquitin ligase
FYN FYN proto-oncogene, Src family tyrosine kinase
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL2 interleukin 2
IL21R interleukin 21 receptor
IL2RG interleukin 2 receptor, gamma
IL6ST interleukin 6 signal transducer
ITPKB inositol-trisphosphate 3-kinase B
LAT linker for activation of T cells
LCK LCK proto-oncogene, Src family tyrosine kinase
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
NFKBID nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
ORAI1 ORAI calcium release-activated calcium modulator 1
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPRC protein tyrosine phosphatase, receptor type, C
WAS Wiskott-Aldrich syndrome
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa