abnormal t follicular helper cell morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of a CD4-positive, CXCR5-positive, CCR7-negative alpha-beta T cell located in follicles of secondary lymph nodes that expresses high levels of BCL-6, ICOS and PD1 and stimulate follicular B cells to undergo class-switching and antibody production (Mammalian Phenotype Ontology, MP_0010184)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0010184
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Genes

9 gene mutations causing the abnormal t follicular helper cell morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
BATF basic leucine zipper transcription factor, ATF-like
BCL6 B-cell CLL/lymphoma 6
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
ITFG2 integrin alpha FG-GAP repeat containing 2
PNP purine nucleoside phosphorylase
RC3H1 ring finger and CCCH-type domains 1
SCARF1 scavenger receptor class F, member 1
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TNIP1 TNFAIP3 interacting protein 1