abnormal t cell subpopulation ratio Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description deviation from the standard ratios of T cell subpopulations (e.g. double positive to single positive ratio) compared to control samples (Mammalian Phenotype Ontology, MP_0003944)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0003944
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30 gene mutations causing the abnormal t cell subpopulation ratio phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ARNTL aryl hydrocarbon receptor nuclear translocator-like
CCL25 chemokine (C-C motif) ligand 25
CCR9 chemokine (C-C motif) receptor 9
CD4 CD4 molecule
CD8A CD8a molecule
CD8B CD8b molecule
CIITA class II, major histocompatibility complex, transactivator
E2F2 E2F transcription factor 2
FOXP3 forkhead box P3
IL7 interleukin 7
IL7R interleukin 7 receptor
ITGAD integrin, alpha D
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
JAK3 Janus kinase 3
LAT linker for activation of T cells
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPRC protein tyrosine phosphatase, receptor type, C
RUNX1 runt-related transcription factor 1
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin
SPI1 Spi-1 proto-oncogene
TCF3 transcription factor 3
TNF tumor necrosis factor
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
TSC22D3 TSC22 domain family, member 3
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZEB1 zinc finger E-box binding homeobox 1