abnormal synaptic plasticity Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description anomaly in the ability of a synapse to change its strength as a result of successive activations (Mammalian Phenotype Ontology, MP_0004859)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0004859
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44 gene mutations causing the abnormal synaptic plasticity phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADCY1 adenylate cyclase 1 (brain)
ADD2 adducin 2 (beta)
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9
BDNF brain-derived neurotrophic factor
BTBD9 BTB (POZ) domain containing 9
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CLCN3 chloride channel, voltage-sensitive 3
CLIP2 CAP-GLY domain containing linker protein 2
CNR1 cannabinoid receptor 1 (brain)
DLG4 discs, large homolog 4 (Drosophila)
DPYSL4 dihydropyrimidinase-like 4
DRD1 dopamine receptor D1
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ESR2 estrogen receptor 2 (ER beta)
FOXP2 forkhead box P2
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIA2 glutamate receptor, ionotropic, AMPA 2
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GRN granulin
KIF17 kinesin family member 17
KSR1 kinase suppressor of ras 1
MAP6 microtubule-associated protein 6
NLGN3 neuroligin 3
NRGN neurogranin (protein kinase C substrate, RC3)
NRP2 neuropilin 2
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PCP4 Purkinje cell protein 4
PICK1 protein interacting with PRKCA 1
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLAT plasminogen activator, tissue
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RGS14 regulator of G-protein signaling 14
RIMS1 regulating synaptic membrane exocytosis 1
SHANK3 SH3 and multiple ankyrin repeat domains 3
SLC8A2 solute carrier family 8 (sodium/calcium exchanger), member 2
STX1A syntaxin 1A (brain)
SYNGAP1 synaptic Ras GTPase activating protein 1
SYNGR1 synaptogyrin 1
TNC tenascin C
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
VLDLR very low density lipoprotein receptor