abnormal spleen marginal sinus morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of the border region surrounding the spleen B cell follicles and the periarteriolar lymphoid sheath (PALS) that separates it from the marginal zone that mediates lymphocyte entry into the white pulp from the blood (Mammalian Phenotype Ontology, MP_0002363)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0002363
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Genes

4 gene mutations causing the abnormal spleen marginal sinus morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CCR7 chemokine (C-C motif) receptor 7
IGHM immunoglobulin heavy constant mu
NKX2-3 NK2 homeobox 3
TNF tumor necrosis factor