abnormal spinal cord dorsal column morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of the wedge-shaped fiber bundle of white matter in the dorsomedial side of the spinal cord that is made up of the fasciculus gracilis and fasciculus cuneatus; it is part of the ascending posterior column-medial lemniscus pathway that is important for well-localized fine touch and conscious proprioception (Mammalian Phenotype Ontology, MP_0009677)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0009677
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Genes

11 gene mutations causing the abnormal spinal cord dorsal column morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CHN1 chimerin 1
DCC DCC netrin 1 receptor
EPHA4 EPH receptor A4
ISPD isoprenoid synthase domain containing
NPR2 natriuretic peptide receptor 2
NRP2 neuropilin 2
NTN1 netrin 1
RUNX3 runt-related transcription factor 3
TENM4 teneurin transmembrane protein 4
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UNC5C unc-5 homolog C (C. elegans)