abnormal secondary ovarian follicle morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly in the ovarian follicle in which the primary oocyte attains its full size and is surrounded by an extracellular glycoprotein layer (zona pellucida) that separates it from a peripheral layer of follicular cells permeated by one or more fluid-filled antra; the primary oocyte occupies the cumulus oophorus while the theca of the follicle develops into internal and external layers (Mammalian Phenotype Ontology, MP_0009363)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0009363
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Genes

21 gene mutations causing the abnormal secondary ovarian follicle morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AKT2 v-akt murine thymoma viral oncogene homolog 2
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CSF1 colony stimulating factor 1 (macrophage)
ESR1 estrogen receptor 1
FADS2 fatty acid desaturase 2
FST follistatin
GNRHR gonadotropin-releasing hormone receptor
MCM8 minichromosome maintenance complex component 8
NOBOX NOBOX oogenesis homeobox
NPC1 Niemann-Pick disease, type C1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PABPC1L poly(A) binding protein, cytoplasmic 1-like
PTPN6 protein tyrosine phosphatase, non-receptor type 6
SGPL1 sphingosine-1-phosphate lyase 1
SRY sex determining region Y
TBPL2 TATA box binding protein like 2
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
UBB ubiquitin B
WWOX WW domain containing oxidoreductase
ZP2 zona pellucida glycoprotein 2 (sperm receptor)
ZP3 zona pellucida glycoprotein 3 (sperm receptor)