abnormal sebocyte morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of the highly specialized, sebum-producing epithelial cells of the sebaceous glands that release their content by rupture of the cell membrane and cellular degradation (holocrine secretion); these cells are most commonly found in the skin in association with hair follicles (forming the pilosebaceous unit), where they arise from hair follicle keratinocytes, but there are also sebaceous glands not associated with a hair follicle; the latter have special functions as secretion of pheromones or corneal protection (Mammalian Phenotype Ontology, MP_0013375)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0013375
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Genes

4 gene mutations causing the abnormal sebocyte morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
GJB6 gap junction protein, beta 6, 30kDa
HR hair growth associated
PLCD1 phospholipase C, delta 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)