abnormal sciatic nerve morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of the nerve which originates in the lumbar and sacral spinal cord (L4 to S3) and supplies motor and sensory innervation to the lower extremity (Mammalian Phenotype Ontology, MP_0002651)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0002651
Similar Terms
Downloads & Tools

Genes

31 gene mutations causing the abnormal sciatic nerve morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADGRG6 adhesion G protein-coupled receptor G6
AIRE autoimmune regulator
APOE apolipoprotein E
CLP1 cleavage and polyadenylation factor I subunit 1
DST dystonin
EBF2 early B-cell factor 2
EGR2 early growth response 2
FIG4 FIG4 phosphoinositide 5-phosphatase
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GALC galactosylceramidase
GARS glycyl-tRNA synthetase
LAMA4 laminin, alpha 4
LARGE like-glycosyltransferase
LGI4 leucine-rich repeat LGI family, member 4
LMNA lamin A/C
LPAR1 lysophosphatidic acid receptor 1
LPIN1 lipin 1
MTMR2 myotubularin related protein 2
NFASC neurofascin
NGFR nerve growth factor receptor
NRD1 nardilysin (N-arginine dibasic convertase)
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
POU3F1 POU class 3 homeobox 1
RND3 Rho family GTPase 3
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SPTBN4 spectrin, beta, non-erythrocytic 4
VEGFA vascular endothelial growth factor A
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)