|Dataset||MPO Gene-Phenotype Associations|
|Category||disease or phenotype associations|
|Description||any anomaly in the adhesive properties of glomerular podocytes, resulting in abnormal cell to cell and cell to extracellular matrix (ECM) interactions; podocytes adhere tightly to ECM components of the glomerular basement membrane via an integrin-laminin-actin axis to maintain a functional filtration barrier in the presence of mechanical stress (Mammalian Phenotype Ontology, MP_0011864)|
|Downloads & Tools|
1 gene mutations causing the abnormal podocyte adhesion phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.
|ACTN4||actinin, alpha 4|