|Dataset||MPO Gene-Phenotype Associations|
|Category||disease or phenotype associations|
|Description||any structural anomaly in the series of transverse folds (ridges) of the mucosa located on the anterior third part of the secondary (hard) palate of most mammalian species; rugae are present on each side of the median palatal raphe and behind the incisive papillae, but their number and arrangement are species specific; together with the teeth and the tongue, rugae take part in mastication by helping to sense, hold and mash the food; rugae harbor various types of intraepithelial sensory structures (such as Merckel cells, corpuscular endings and free nerve endings), and play a sensory role when the food is pressed by the tongue against the hard palate (Mammalian Phenotype Ontology, MP_0009652)|
|Downloads & Tools|
7 gene mutations causing the abnormal palatal rugae morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.