abnormal myeloid dendritic cell morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of phagocytic cells of the myeloid lineage that capture antigens in the periphery and then migrate to the lymphoid organs and secrete cytokines to initiate immune responses (Mammalian Phenotype Ontology, MP_0006173)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0006173
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Genes

23 gene mutations causing the abnormal myeloid dendritic cell morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AHR aryl hydrocarbon receptor
BATF3 basic leucine zipper transcription factor, ATF-like 3
BCL3 B-cell CLL/lymphoma 3
CCR6 chemokine (C-C motif) receptor 6
CD207 CD207 molecule, langerin
CLEC10A C-type lectin domain family 10, member A
CSF1 colony stimulating factor 1 (macrophage)
CSF1R colony stimulating factor 1 receptor
FLT3LG fms-related tyrosine kinase 3 ligand
GPR183 G protein-coupled receptor 183
IL10 interleukin 10
IL2RG interleukin 2 receptor, gamma
IL34 interleukin 34
ITGB6 integrin, beta 6
JAK3 Janus kinase 3
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
RUNX3 runt-related transcription factor 3
SPPL2A signal peptide peptidase like 2A
STK4 serine/threonine kinase 4
TGFB1 transforming growth factor, beta 1
TNFAIP8L2 tumor necrosis factor, alpha-induced protein 8-like 2
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11