abnormal motor neuron innervation pattern Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any changes in the placement, morphology or number of motor nerve fibers to an effector motor tissue, or failure of refinement of neuronal connections during development (Mammalian Phenotype Ontology, MP_0000940)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0000940
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Genes

30 gene mutations causing the abnormal motor neuron innervation pattern phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ALCAM activated leukocyte cell adhesion molecule
ALS2 amyotrophic lateral sclerosis 2 (juvenile)
CHAT choline O-acetyltransferase
CHN1 chimerin 1
CHRNG cholinergic receptor, nicotinic, gamma (muscle)
CLIP3 CAP-GLY domain containing linker protein 3
CLP1 cleavage and polyadenylation factor I subunit 1
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
ECEL1 endothelin converting enzyme-like 1
EFNB3 ephrin-B3
EPHA4 EPH receptor A4
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB4 erb-b2 receptor tyrosine kinase 4
ETV4 ets variant 4
FBXO45 F-box protein 45
GAN gigaxonin
GDNF glial cell derived neurotrophic factor
GFRA1 GDNF family receptor alpha 1
ISL2 ISL LIM homeobox 2
LMNB1 lamin B1
MET MET proto-oncogene, receptor tyrosine kinase
MUSK muscle, skeletal, receptor tyrosine kinase
NKX2-8 NK2 homeobox 8
NRG1 neuregulin 1
RET ret proto-oncogene
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7
TOP2B topoisomerase (DNA) II beta 180kDa
UNC5C unc-5 homolog C (C. elegans)