abnormal motile cilium physiology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of a cilium which has a variable arrangement of axonemal microtubules, contains molecular motors, and beats with a characteristic whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface; motile cilia are typically found in multiple copies on epithelial cells that line the lumenal ducts of various tissues and may also function as sensory organelles (Mammalian Phenotype Ontology, MP_0013209)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0013209
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23 gene mutations causing the abnormal motile cilium physiology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AK7 adenylate kinase 7
ARL6 ADP-ribosylation factor-like 6
ARMC4 armadillo repeat containing 4
C1ORF127 chromosome 1 open reading frame 127
CCDC151 coiled-coil domain containing 151
CCDC39 coiled-coil domain containing 39
CLUAP1 clusterin associated protein 1
CNBD2 cyclic nucleotide binding domain containing 2
DAW1 dynein assembly factor with WDR repeat domains 1
DNAAF2 dynein, axonemal, assembly factor 2
DNAAF3 dynein, axonemal, assembly factor 3
DNAH11 dynein, axonemal, heavy chain 11
DNAH5 dynein, axonemal, heavy chain 5
DNAI1 dynein, axonemal, intermediate chain 1
DYX1C1 dyslexia susceptibility 1 candidate 1
EFHC1 EF-hand domain (C-terminal) containing 1
HYDIN HYDIN, axonemal central pair apparatus protein
NME7 NME/NM23 family member 7
PCSK5 proprotein convertase subtilisin/kexin type 5
ROPN1L rhophilin associated tail protein 1-like
SPEF2 sperm flagellar 2
TEKT2 tektin 2 (testicular)
TTLL1 tubulin tyrosine ligase-like family member 1