abnormal mitotic spindle assembly checkpoint Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description an anomaly in the process that normally prevents inaccurate segregation of chromosome by inhibiting cell-cycle progression in response to a signal generated by mitotic spindle damage or by chromosomes that have not attached to microtubules (Mammalian Phenotype Ontology, MP_0009762)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0009762
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Genes

6 gene mutations causing the abnormal mitotic spindle assembly checkpoint phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
LMNA lamin A/C
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
TPX2 TPX2, microtubule-associated