abnormal mitochondrial atp synthesis coupled electron transport Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description anomaly in the transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP, as it occurs in the mitochondrial inner membrane and mediated by multisubunit enzyme complexes known as complex I-IV (Mammalian Phenotype Ontology, MP_0010956)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0010956
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26 gene mutations causing the abnormal mitochondrial atp synthesis coupled electron transport phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CISD1 CDGSH iron sulfur domain 1
COQ9 coenzyme Q9
COX17 COX17 cytochrome c oxidase copper chaperone
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15
DNM1L dynamin 1-like
GAMT guanidinoacetate N-methyltransferase
HSPD1 heat shock 60kDa protein 1 (chaperonin)
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1
LCLAT1 lysocardiolipin acyltransferase 1
MT-ND6 NADH dehydrogenase, subunit 6 (complex I)
MTERF2 mitochondrial transcription termination factor 2
MTFR1 mitochondrial fission regulator 1
NDUFAF2 NADH dehydrogenase (ubiquinone) complex I, assembly factor 2
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
NOA1 nitric oxide associated 1
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2
PINK1 PTEN induced putative kinase 1
POLG polymerase (DNA directed), gamma
PTCD2 pentatricopeptide repeat domain 2
SCO2 SCO2 cytochrome c oxidase assembly protein
TFAM transcription factor A, mitochondrial
TGM2 transglutaminase 2
THRA thyroid hormone receptor, alpha
TK2 thymidine kinase 2, mitochondrial
UCP3 uncoupling protein 3 (mitochondrial, proton carrier)