abnormal mismatch repair Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any functional anomaly in the system that promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination (Mammalian Phenotype Ontology, MP_0009797)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0009797
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Genes

5 gene mutations causing the abnormal mismatch repair phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
EXO1 exonuclease 1
MSH2 mutS homolog 2
MSH3 mutS homolog 3
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
TDG thymine-DNA glycosylase