abnormal middle ear morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of any components of the tympanic cavity or its ossicles (Mammalian Phenotype Ontology, MP_0000049)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0000049
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Genes

70 gene mutations causing the abnormal middle ear morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ANKH ANKH inorganic pyrophosphate transport regulator
BMP7 bone morphogenetic protein 7
BMPER BMP binding endothelial regulator
CHD7 chromodomain helicase DNA binding protein 7
CHRD chordin
DLX1 distal-less homeobox 1
DLX2 distal-less homeobox 2
DLX5 distal-less homeobox 5
DLX6 distal-less homeobox 6
DUSP6 dual specificity phosphatase 6
E2F4 E2F transcription factor 4, p107/p130-binding
ECE1 endothelin converting enzyme 1
EDN1 endothelin 1
EDNRA endothelin receptor type A
EFNB1 ephrin-B1
EMX2 empty spiracles homeobox 2
EYA1 EYA transcriptional coactivator and phosphatase 1
EYA4 EYA transcriptional coactivator and phosphatase 4
FBLN1 fibulin 1
FBXO11 F-box protein 11
FGF9 fibroblast growth factor 9
FGFR1 fibroblast growth factor receptor 1
FGFR3 fibroblast growth factor receptor 3
FOXC2 forkhead box C2
FOXI3 forkhead box I3
GAS1 growth arrest-specific 1
GBX2 gastrulation brain homeobox 2
GDF6 growth differentiation factor 6
GJA1 gap junction protein, alpha 1, 43kDa
GLI2 GLI family zinc finger 2
GSC goosecoid homeobox
HAND2 heart and neural crest derivatives expressed 2
HAPLN1 hyaluronan and proteoglycan link protein 1
HMX1 H6 family homeobox 1
HOXA1 homeobox A1
HOXA2 homeobox A2
HSPG2 heparan sulfate proteoglycan 2
ISL1 ISL LIM homeobox 1
MECOM MDS1 and EVI1 complex locus
MSX1 msh homeobox 1
MUC5B mucin 5B, oligomeric mucus/gel-forming
NABP2 nucleic acid binding protein 2
NAGLU N-acetylglucosaminidase, alpha
NKX3-2 NK3 homeobox 2
NOG noggin
OSR2 odd-skipped related transciption factor 2
OTX2 orthodenticle homeobox 2
PAX8 paired box 8
PAX9 paired box 9
PBX1 pre-B-cell leukemia homeobox 1
PGAP1 post-GPI attachment to proteins 1
PITX1 paired-like homeodomain 1
POU3F3 POU class 3 homeobox 3
POU3F4 POU class 3 homeobox 4
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator
PRRX1 paired related homeobox 1
RARA retinoic acid receptor, alpha
ROR2 receptor tyrosine kinase-like orphan receptor 2
RPL38 ribosomal protein L38
RSPO2 R-spondin 2
SALL4 spalt-like transcription factor 4
SH3PXD2B SH3 and PX domains 2B
SIX1 SIX homeobox 1
TBX1 T-box 1
TCOF1 Treacher Collins-Franceschetti syndrome 1
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TGIF1 TGFB-induced factor homeobox 1
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TSHZ1 teashirt zinc finger homeobox 1
WDR19 WD repeat domain 19