abnormal midbrain roof plate morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of the mesencephalic roof plate, including the caudal and rostral part of the midbrain roof (Mammalian Phenotype Ontology, MP_0006103)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0006103
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Genes

31 gene mutations causing the abnormal midbrain roof plate morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AP3B1 adaptor-related protein complex 3, beta 1 subunit
CD247 CD247 molecule
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EN1 engrailed homeobox 1
EN2 engrailed homeobox 2
FGF17 fibroblast growth factor 17
FGF8 fibroblast growth factor 8 (androgen-induced)
FGFR1 fibroblast growth factor receptor 1
FOXB1 forkhead box B1
GBX2 gastrulation brain homeobox 2
GLI3 GLI family zinc finger 3
IREB2 iron-responsive element binding protein 2
KAT6B K(lysine) acetyltransferase 6B
LMX1B LIM homeobox transcription factor 1, beta
LRP6 low density lipoprotein receptor-related protein 6
MID1 midline 1
NGFR nerve growth factor receptor
OTX1 orthodenticle homeobox 1
OTX2 orthodenticle homeobox 2
PAX2 paired box 2
PAX5 paired box 5
POU4F2 POU class 4 homeobox 2
STRBP spermatid perinuclear RNA binding protein
SUZ12 SUZ12 polycomb repressive complex 2 subunit
TAL2 T-cell acute lymphocytic leukemia 2
TENM2 teneurin transmembrane protein 2
TFAP2D transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
UNC5C unc-5 homolog C (C. elegans)
VAC14 Vac14 homolog (S. cerevisiae)
WNT1 wingless-type MMTV integration site family, member 1