abnormal macrophage differentiation Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description atypical production of or inability to produce the large mononuclear phagocytes which differentiate from monocytes, are typically resident in a particular tissue, and capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells (Mammalian Phenotype Ontology, MP_0008113)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008113
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Genes

4 gene mutations causing the abnormal macrophage differentiation phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CSF1R colony stimulating factor 1 receptor
IKZF1 IKAROS family zinc finger 1 (Ikaros)
RB1 retinoblastoma 1
SPI1 Spi-1 proto-oncogene