abnormal macrophage antigen presentation Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description anomaly in the ability of macrophage phagocytic cells to process and present antigen to T lymphocytes (Mammalian Phenotype Ontology, MP_0002454)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0002454
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Genes

8 gene mutations causing the abnormal macrophage antigen presentation phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CIITA class II, major histocompatibility complex, transactivator
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IFNG interferon, gamma
NUP98 nucleoporin 98kDa
RFX5 regulatory factor X, 5 (influences HLA class II expression)
STAT1 signal transducer and activator of transcription 1, 91kDa