abnormal lymph node cortex morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly in the outer area of the lymph node that has B and T cell domains (Mammalian Phenotype Ontology, MP_0002343)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0002343
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Genes

44 gene mutations causing the abnormal lymph node cortex morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
BCL3 B-cell CLL/lymphoma 3
BCL6 B-cell CLL/lymphoma 6
BHLHE40 basic helix-loop-helix family, member e40
BTK Bruton agammaglobulinemia tyrosine kinase
CCR7 chemokine (C-C motif) receptor 7
CD37 CD37 molecule
CD4 CD4 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
CTSV cathepsin V
CXCL13 chemokine (C-X-C motif) ligand 13
CXCR4 chemokine (C-X-C motif) receptor 4
FOXN1 forkhead box N1
FOXP3 forkhead box P3
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
HR hair growth associated
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IRF4 interferon regulatory factor 4
KLHL6 kelch-like family member 6
LAT linker for activation of T cells
LTA lymphotoxin alpha
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NOD2 nucleotide-binding oligomerization domain containing 2
PBX1 pre-B-cell leukemia homeobox 1
PI16 peptidase inhibitor 16
POU2AF1 POU class 2 associating factor 1
PRKCD protein kinase C, delta
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PTEN phosphatase and tensin homolog
RASSF5 Ras association (RalGDS/AF-6) domain family member 5
RC3H1 ring finger and CCCH-type domains 1
RRAS2 related RAS viral (r-ras) oncogene homolog 2
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SOCS1 suppressor of cytokine signaling 1
TNF tumor necrosis factor
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TRAF2 TNF receptor-associated factor 2
UNC13D unc-13 homolog D (C. elegans)