abnormal long term potentiation Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description alterations in a persistent robust synaptic response induced by synchronous stimulation of pre- and postsynaptic cells (Mammalian Phenotype Ontology, MP_0002207)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0002207
Similar Terms
Downloads & Tools

Genes

168 gene mutations causing the abnormal long term potentiation phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
ADD2 adducin 2 (beta)
AFF2 AF4/FMR2 family, member 2
AKAP5 A kinase (PRKA) anchor protein 5
AP3M2 adaptor-related protein complex 3, mu 2 subunit
APP amyloid beta (A4) precursor protein
ARC activity-regulated cytoskeleton-associated protein
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9
ASIC1 acid sensing (proton gated) ion channel 1
ATAD1 ATPase family, AAA domain containing 1
ATRX alpha thalassemia/mental retardation syndrome X-linked
ATXN1 ataxin 1
B3GAT1 beta-1,3-glucuronyltransferase 1
BAIAP2 BAI1-associated protein 2
BCAN brevican
BDNF brain-derived neurotrophic factor
BTBD9 BTB (POZ) domain containing 9
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CACNG8 calcium channel, voltage-dependent, gamma subunit 8
CALB2 calbindin 2
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CCR7 chemokine (C-C motif) receptor 7
CD247 CD247 molecule
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CHRD chordin
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CHST10 carbohydrate sulfotransferase 10
CNGA2 cyclic nucleotide gated channel alpha 2
CNR1 cannabinoid receptor 1 (brain)
CPEB1 cytoplasmic polyadenylation element binding protein 1
CPLX2 complexin 2
CREB1 cAMP responsive element binding protein 1
CRMP1 collapsin response mediator protein 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNND2 catenin (cadherin-associated protein), delta 2
CYBB cytochrome b-245, beta polypeptide
DGCR8 DGCR8 microprocessor complex subunit
DGKB diacylglycerol kinase, beta 90kDa
DGKE diacylglycerol kinase, epsilon 64kDa
DISC1 disrupted in schizophrenia 1
DLG3 discs, large homolog 3 (Drosophila)
DLG4 discs, large homolog 4 (Drosophila)
DOC2A double C2-like domains, alpha
DPP6 dipeptidyl-peptidase 6
DPYSL4 dihydropyrimidinase-like 4
EFNA3 ephrin-A3
EFNB3 ephrin-B3
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
EPHA4 EPH receptor A4
ESR2 estrogen receptor 2 (ER beta)
FMR1 fragile X mental retardation 1
FYN FYN proto-oncogene, Src family tyrosine kinase
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5
GAL galanin/GMAP prepropeptide
GFAP glial fibrillary acidic protein
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GRASP GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIA2 glutamate receptor, ionotropic, AMPA 2
GRIA3 glutamate receptor, ionotropic, AMPA 3
GRIK1 glutamate receptor, ionotropic, kainate 1
GRIK2 glutamate receptor, ionotropic, kainate 2
GRIK3 glutamate receptor, ionotropic, kainate 3
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GRM1 glutamate receptor, metabotropic 1
GRM5 glutamate receptor, metabotropic 5
GRN granulin
HDAC2 histone deacetylase 2
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
ICAM5 intercellular adhesion molecule 5, telencephalin
ITM2B integral membrane protein 2B
ITPKA inositol-trisphosphate 3-kinase A
KALRN kalirin, RhoGEF kinase
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNH3 potassium channel, voltage gated eag related subfamily H, member 3
KCNIP3 Kv channel interacting protein 3, calsenilin
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KIF17 kinesin family member 17
KSR1 kinase suppressor of ras 1
LAMA2 laminin, alpha 2
LEPR leptin receptor
LIMK1 LIM domain kinase 1
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
MAN2B1 mannosidase, alpha, class 2B, member 1
MAPK3 mitogen-activated protein kinase 3
MAPK9 mitogen-activated protein kinase 9
MAPT microtubule-associated protein tau
MAS1 MAS1 proto-oncogene, G protein-coupled receptor
MBD1 methyl-CpG binding domain protein 1
MECP2 methyl CpG binding protein 2
MMP9 matrix metallopeptidase 9
NBEA neurobeachin
NCAN neurocan
NCF1 neutrophil cytosolic factor 1
NELL2 NEL-like 2 (chicken)
NETO1 neuropilin (NRP) and tolloid (TLL)-like 1
NOS1 nitric oxide synthase 1 (neuronal)
NOVA2 neuro-oncological ventral antigen 2
NRG1 neuregulin 1
NRGN neurogranin (protein kinase C substrate, RC3)
NRXN3 neurexin 3
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OPRL1 opiate receptor-like 1
OPRM1 opioid receptor, mu 1
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PINK1 PTEN induced putative kinase 1
PLAT plasminogen activator, tissue
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRKCG protein kinase C, gamma
PRNP prion protein
PSAP prosaposin
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTN pleiotrophin
PTPRD protein tyrosine phosphatase, receptor type, D
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1
RARB retinoic acid receptor, beta
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RAVER1 ribonucleoprotein, PTB-binding 1
RGS14 regulator of G-protein signaling 14
RIMS1 regulating synaptic membrane exocytosis 1
RIN1 Ras and Rab interactor 1
RYR3 ryanodine receptor 3
SCT secretin
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SHANK2 SH3 and multiple ankyrin repeat domains 2
SHANK3 SH3 and multiple ankyrin repeat domains 3
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC8A2 solute carrier family 8 (sodium/calcium exchanger), member 2
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SP4 Sp4 transcription factor
SPRED1 sprouty-related, EVH1 domain containing 1
SRR serine racemase
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
STX1A syntaxin 1A (brain)
STXBP5 syntaxin binding protein 5 (tomosyn)
SYNGAP1 synaptic Ras GTPase activating protein 1
SYNPO synaptopodin
THY1 Thy-1 cell surface antigen
TMOD2 tropomodulin 2 (neuronal)
TNC tenascin C
TRIB2 tribbles pseudokinase 2
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSC2 tuberous sclerosis 2
TYROBP TYRO protein tyrosine kinase binding protein
UBE3A ubiquitin protein ligase E3A
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
VDAC1 voltage-dependent anion channel 1
VLDLR very low density lipoprotein receptor
WASF1 WAS protein family, member 1
WWC1 WW and C2 domain containing 1